High testosterone is like … finasteride? Say what!

[Forty2]

Madman, would troches have similar pharmacokinetics to the Androderm patch?

 

[Cataceous]

Madman, would troches have similar pharmacokinetics to the Androderm patch?

No, they are more like Natesto. There's a rapid spike in levels followed by a relatively swift decline. As a standalone TRT method they would need to be used at least 2-3 times daily.

 

[Gianluca]

At this point the blend Propionate/CYP or ENA to take daily, may be probably the best physiological option to get test into circulation considering metabolites conversion with some daily fluctuation in T, without letting testosterone dropping too low a couple of times in 24hr like the orals do.

Cataceous figured this out already sometime ago. @Cataceous what ratio of Prop : CYP do you use?
how many mg/ml is the solution?

 

[Cataceous]

...
Cataceous figured this out already sometime ago. @Cataceous what ratio of Prop : CYP do you use?
how many mg/ml is the solution?

When blending propionate with either enanthate or cypionate I found that getting half of the testosterone from each ester gives a diurnal variation in levels that is at the high end of normal, around +/-25% about the mean, or a 40% drop from peak to trough. We discussed a lot of the nuts and bolts in this thread:

W

Thread 'Tips on how to blend propionate with enanthate (or cypionate)?'

May 26, 2021

I have been having some success with low dose daily propionate for the last several months. Dose levels have ranged from 8-10 mg injected every morning after waking. Overall, it has been a far better experience than my previous cypionate protocol of 80-100 per week (split every 3.5 days). Evidently, I am one of those guys who responds better to daily variation versus steady state (along with smaller, more frequent doses).

However, straight propionate hits hard and fast as you many of you know, resulting in a steep daily drop-off from peak to trough. I enjoy the energy it brings, but it...

• Willyt
• blend daily low dose propionate
• Replies: 137
• Forum: Testosterone Basics & Questions

I use 0.3 cc syringes, which give me a resolution of 0.005 mL. This sets the granularity of my dose sizes. My enanthate is 300 mg/mL and my propionate is 100 mg/mL. The 4:3 ratio of ester weights translates to a 4:9 ratio of volumes. A typical batch might be 0.44 mL TE and 0.99 mL TP. Each mL contains 92.3 mg TE and 69.2 mg TP. This also means each mL contains 66.5 mg T from TE and 57.9 mg T from TP. You can now see that my current dose of 3.2 mg TE + 2.4 mg TP corresponds to a dose size of 0.035 mL. In the past I've also used doses of 0.03 and 0.04 mL.
...

I've recently made the switch to a micronized testosterone suspension, 3 injections daily, with the intent of getting away from enclomiphene and reproducing what occurs with Natesto. Preliminary results are encouraging, with a morning trough level of over 300 ng/dL seemingly being mostly from endogenous production.

 

[Forty2]

I've recently made the switch to a micronized testosterone suspension, 3 injections daily, with the intent of getting away from enclomiphene and reproducing what occurs with Natesto. Preliminary results are encouraging, with a morning trough level of over 300 ng/dL seemingly being mostly from endogenous proproduction

Do you think it would be possible to combine those 3 daily injections of testosterone suspension with a low dose of hCG, such as 150iu eod and still maintain some LH production?

 

[Gianluca]

When blending propionate with either enanthate or cypionate I found that getting half of the testosterone from each ester gives a diurnal variation in levels that is at the high end of normal, around +/-25% about the mean, or a 40% drop from peak to trough. We discussed a lot of the nuts and bolts in this thread:

W

Thread 'Tips on how to blend propionate with enanthate (or cypionate)?'

May 26, 2021

I have been having some success with low dose daily propionate for the last several months. Dose levels have ranged from 8-10 mg injected every morning after waking. Overall, it has been a far better experience than my previous cypionate protocol of 80-100 per week (split every 3.5 days). Evidently, I am one of those guys who responds better to daily variation versus steady state (along with smaller, more frequent doses).

However, straight propionate hits hard and fast as you many of you know, resulting in a steep daily drop-off from peak to trough. I enjoy the energy it brings, but it...

• Willyt
• blend daily low dose propionate
• Replies: 137
• Forum: Testosterone Basics & Questions

I've recently made the switch to a micronized testosterone suspension, 3 injections daily, with the intent of getting away from enclomiphene and reproducing what occurs with Natesto. Preliminary results are encouraging, with a morning trough level of over 300 ng/dL seemingly being mostly from endogenous production.

thanks for sharing!

 

[Cataceous]

Do you think it would be possible to combine those 3 daily injections of testosterone suspension with a low dose of hCG, such as 150iu eod and still maintain some LH production?

It is possible. Assuming the injections are comparable to Natesto, which is not a given, then that modest HPTA suppression combined with a little more from hCG might still allow for some LH production. It's probably a situation where different individuals could see different outcomes.

 

[Mastodont]

I'm planning on trying out testavan gel soon, since studies claim it comes back to baseline after 12hrs, applied in the morning, there might be some endogenous activity during the night, at the very least large daily fluctuation in levels. Will take LH in the morning, who knows it might not be at 0