Help adjusting daily Testosterone Dosage

optimizely · Oct 16, 2018

I just got my bloodwork back after switiching to daily test cyp for 6 weeks.

I’m taking 16mg/day with .25mg of anastrozole EOD.

Free T is 30.1 pg/ml
Total T 912.3 ng/dl
Estradiol, Sensitive 19.8 pg/ml
SHBG 15.9 nmol/L

I have a couple questions because even though my lab work may appear spectacular I don’t feel optimized have insomnia, slight ed, and low libido.

Is my free T too high for my low SHBG. What Free T number should I be aiming for? And how much should I cut my daily dose by to achieve an optimal free T number.

I’m also curious if my estrogen is still too high...since low SHBG and all.

Vince · Oct 17, 2018

But just looking at your levels, I would say everything is perfect. It's too bad you don't feel good.

optimizely · Oct 17, 2018

I’m thinking my estrogen is too high for my low SHBG. Vince Carter says he feels the best when his estrogen is 6 and he has a SHBG of 12. I’m thinking us guys need very little estrogen.

Vince · Oct 17, 2018

Your estrogen level is at 19.8 and your shbg is at 15.9, you can't get much closer than that.

blackebob · Oct 17, 2018

I have numbers close to that. I am dropping my dose from .13cc(26mg) ED to .08cc(16mg) ED. I have been at .10(20mg) for 4 weekes now bettor morning wood, waking up refreshed at 5am, libido strong. I have been told to not worry about TT, but instead to shoot for free T at the top of the range, in range though. I am also shooting for my E close to my shbg. I can tell when my E is higher, upper twenties low thirties even. I think you should get your free E tested also. I believe it plays a role like free T.

optimizely · Oct 17, 2018

I think if I can get my estrogen into single digits that might resolve my issues. I will report back and see if that helps. Is it also possible that daily injections just aren’t for everybody?

optimizely · Oct 17, 2018

blackebob said:
I have numbers close to that. I am dropping my dose from .13cc(26mg) ED to .08cc(16mg) ED. I have been at .10(20mg) for 4 weekes now bettor morning wood, waking up refreshed at 5am, libido strong. I have been told to not worry about TT, but instead to shoot for free T at the top of the range, in range though. I am also shooting for my E close to my shbg. I can tell when my E is higher, upper twenties low thirties even. I think you should get your free E tested also. I believe it plays a role like free T.

I completely agree with you. I’ve just held off on testing free E due to the cost and Dr. Crisler really says there is no need when you can use SHBG and estradiol sensitive to make an educated decision. What Free T number do you shoot for? I’m thinking with low SHBG I may be better around 25 rather than 30 what I have now.

Vince Carter · Oct 17, 2018

My last Free E was .18 (<0.45, is the lab range).

Affordability is a factor in that test.

Vince Carter · Oct 17, 2018

Too your situation makes more sense and seems clearer when you don't make multiple threads on the same subject.

blackebob · Oct 17, 2018

optimizely said:
I completely agree with you. I’ve just held off on testing free E due to the cost and Dr. Crisler really says there is no need when you can use SHBG and estradiol sensitive to make an educated decision. What Free T number do you shoot for? I’m thinking with low SHBG I may be better around 25 rather than 30 what I have now.

I have had my ultra estrogen come back well in range and my free E was still off the chart. More is not necessarily bettor for me.
Free T close to top of range.

Vince Carter · Oct 17, 2018

blackebob said:
I have had my ultra estrogen come back well in range and my free E was still off the chart. More is not necessarily bettor for me.
Free T close to top of range.

That happened to me, my Free E wouldn't come down under the lab range even though my LC/MS/MS was what the rest would call in range/just fine, which was NOT working for me.

optimizely · Oct 20, 2018

How much do you recommend I cut my daily dose to if I wanna get my free T from 30.1 to 26.5? I’m currently taking 16mg daily and have a Free T of 30.1.