Youre on the right path here...if HCG worked to "backfill" why would anyone need to supplement DHEA or Prog. It mimics LH but there's either a enzyme(?) dysfunction in the Hypo male or it just doesn't mimic well enough to spur that downstream conversion from Cholesterol. It reads well on paper but there are a ton a real world guys that categorically it does not work. There's even been heavy discussion on the compounded HCG vs Pharma HCG, like Pregnyl, being not the same. As in Pregnyl being more effective. Some guys have used both and reported a subjective better response with Pregnyl.I get confused when individuals are taking hcg along with dhea and pregnenolone supplementation.
Predict estradiol, DHT, and free testosterone levels based on total testosterone
This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.
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A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.
Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.
The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.
Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.
DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038