has CPAP machine lowered anyone's hematocrit?

An old study..

Chest. 1990 Mar;97(3):729-30. doi: 10.1378/chest.97.3.729.

Overnight decrease in hematocrit after nasal CPAP treatment in patients with OSA

J Krieger 1, E Sforza, M Barthelmebs, J L Imbs, D Kurtz

Abstract
To clarify the paradox of a decrease in urine and sodium excretion occurring along with the elimination of peripheral edema when patients with obstructive sleep apnea (OSA) are treated with nasal continuous positive airway pressure (CPAP), we investigated the immediate effects of this treatment on the hematocrit and red blood cell count in eight patients with OSA. The hematocrit decreased in all patients, from a mean of 45.6 +/- 1.2 percent to 43.0 +/- 1.4 percent, with a parallel decrease in the red blood cell count from 4.777 +/- 0.168 millions/cu mm to 4.577 +/- 0.174 millions/cu mm (p less than 0.0005, one-tailed, in both cases). These results suggest that nasal CPAP treatment causes a hemodilution in patients with OSA, and are compatible with the hypothesis of an atrial natriuretic peptide-induced fluid shift from the intravascular to the extravascular volume in untreated patients with OSA. The reversal of these changes with CPAP treatment could explain the simultaneous decrease in sodium and urine excretion and the reduction of peripheral edema.
 
ακούστηκε ότι η υψηλή HCT από TRT μπορεί να προκληθεί από άπνοια ύπνου. έχει κατεβάσει κανείς εκεί με CPAP;
Ναι, είχα αιματοκρίτη 58 όταν διαγνώστηκα με υπνική άπνοια. Φορώντας τη μάσκα ο αιματοκρίτης μου έφτασε στα 46 σε δύο μήνες. Φοβερός!!
I was kind of two years into Tr I used to give blood often, now I have to give blood for a year.
 

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Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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