GHK-cu and DHT

[BadassBlues]

Any reason to not do it am and pm?

how many mgs do u inject once in the am?

I’ve been doing 1mg upon waking, and another 1mg prior to bed everyday

No reason that I know of, it may even be better to split the dose. I do it in the morning as a single dose out of convenience. I inject 2 mg.

 

[t_spacemonkey]

anybody can point me to a source for injectable ghk-cu?

 

[BadassBlues]

anybody can point me to a source for injectable ghk-cu?

Good quality, great price.

GHK-cu – 50mg

GHK-cu This product is not intended for weight loss, human consumption, or veterinary use. It is sold for research purposes only. Please handle with care and follow all safety guidelines for the specific chemicals involved. GHK-Cu (glycyl-L-histidyl-L-lysine copper) is a naturally occurring...

nusciencepeptides.com

 

[Gman86]

anybody can point me to a source for injectable ghk-cu?

I’m currently using it from nuscience

GHK-cu – 50mg

GHK-cu This product is not intended for weight loss, human consumption, or veterinary use. It is sold for research purposes only. Please handle with care and follow all safety guidelines for the specific chemicals involved. GHK-Cu (glycyl-L-histidyl-L-lysine copper) is a naturally occurring...

nusciencepeptides.com

 

[t_spacemonkey]

so what is the injection protocol? 2mg/subq1 1x a day (or 1mg/2x day subq?) for 6 weeks at a time?

 

[BadassBlues]

so what is the injection protocol? 2mg/subq1 1x a day (or 1mg/2x day subq?) for 6 weeks at a time?

That is the current discussion. I don't see any downside to twice a day, and hypothetically speaking, it may be beneficial to do so as it may keep it in your system longer.

I dose 2mg once a day in the AM, mainly for convenience as I already do other injections at night.

The 6 week protocol is what Dr. Seeds recommends in his book, Peptide Protocols. But as we have been discussing here, it seems that the chance of copper toxicity at those doses is pretty small, if nonexistent. So it's up to the individual to determine dosage and frequency with those parameters in mind.

 

[Nelson Vergel]

I just found out Empower sells this for hair loss:

GHK-Cu Scalp Solution

Discover the power of GHK-Cu for rejuvenating your skin. Learn about its benefits and how it can improve the appearance of aging skin.

www.empowerpharmacy.com

Based on the available research, GHK-Cu (copper peptide) does not appear to cause sexual dysfunction like finasteride. The key points are:

1. GHK-Cu is a naturally occurring peptide in the human body that has been studied primarily for its potential anti-aging and skin rejuvenation effects. It is not a hormone or hormone-modulating drug like finasteride[1][2].

2. The main mechanism of action of GHK-Cu involves stimulating collagen production, promoting wound healing, and having antioxidant and anti-inflammatory properties[1][2]. This is very different from finasteride, which inhibits the enzyme 5-alpha reductase and alters hormone levels.

3. In the extensive research on GHK-Cu, there do not appear to be any reports of sexual side effects like decreased libido, erectile dysfunction, or ejaculatory problems that are associated with finasteride use[1][2][3].

4. The side effects reported for GHK-Cu are generally mild and include potential skin irritation when applied topically. Systemic side effects are rare when used as directed[3].

5. Finasteride's sexual side effects are thought to be related to its effects on androgens and neurosteroids in the body. GHK-Cu does not have these hormonal effects[6][7][8].

In summary, while finasteride has well-documented potential sexual side effects in some men, there is no evidence that GHK-Cu causes similar issues. The mechanisms and effects of these two compounds are very different. However, as with any supplement or medication, it's always advisable to consult with a healthcare provider before use, especially if you have any pre-existing health conditions or concerns.

Citations:
[1] What Are Peptides? - Peptides Therapy Orchidia Medical Group
[2] Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data - PMC
[3] How Quickly Does Peptide Therapy Start Working? | Priority You
[4] Does Finasteride Cause Erectile Dysfunction? | Wimpole Clinic
[5] GoodRx - Error
[6] Finasteride and sexual side effects - PMC
[7] Persistent sexual side effects of finasteride for male pattern hair loss - PubMed
[8] Global online interest in finasteride sexual side effects - International Journal of Impotence Research
[9] Neuroticism Predicts Anxiety and Depression Disorders
[10] Are Finasteride Side Effects Permanent? - HairScience
[11] Finasteride and Dutasteride for the Treatment of Male Androgenetic Alopecia: A Review of Efficacy and Reproductive Adverse Effects | Published in Georgetown Medical Review

 

[bruin]

No reason that I know of, it may even be better to split the dose. I do it in the morning as a single dose out of convenience. I inject 2 mg.

What is the measurement for reconstitution of 50mg vial. I have conflicting info ranginf from 1ml to 2 ml?
Thanks

 

[Cataceous]

What is the measurement for reconstitution of 50mg vial. I have conflicting info ranginf from 1ml to 2 ml?
Thanks

You can do either depending on what makes it convenient to take the intended dose. With 50 mg/mL you have 0.5 mg/unit in a U-100 insulin syringe. With 50 mg/ 2 mL = 25 mg/mL you have 0.25 mg/unit.

I tend to initially mix 100 mg GHK-Cu with only 1 mL of bacteriostatic water, but my multiple 1 mg daily doses are mixed with other peptides.

 

[bruin]

I tend to initially mix 100 mg GHK-Cu with only 1 mL of bacteriostatic water, but my multiple 1 mg daily doses are mixed with other peptides.

So, I would use a half ml in the 50mg vial, essentially halving the process, there is nothing else being mixed at this time?

 

[Cataceous]

So, I would use a half ml in the 50mg vial, essentially halving the process, there is nothing else being mixed at this time?

What dose size are you targeting? Going with 1 mg/mL is likely more concentrated than you want, especially if you're not using 0.3 cc syringes with half-unit markings. Suppose you're using 1 cc U-100 syringes and want a 2 mg dose. Then you'd be better off with the original dilutions you mentioned, because the unit spacings are pretty small, and you want at least 4-8 units per dose to attain reasonable accuracy.

 

[bruin]

I started a week ago, 1.75 mg in the am in the abs or butt, 6 weeks on/6 weeks off . I have not come across an accepted universal regimen. I find this thread it somewhat help.

Any insight is appreciated

 

[Cataceous]

...
Any insight is appreciated

We're largely on our own with this. There's this frequent argument that we should take breaks, but it seems to be based more on speculation and caution than anything concrete. Assuming copper intake is reasonable, my hope is that as with testosterone, the short half-life and pulsatile delivery of modest amounts will yield benefits with minimal disruption of the endogenous systems.

For what it's worth, I've been injecting 1 mg six times a day for several years. Regarding possible correlations, I perceive improvements in skin quality and the disappearance of some presumably benign subcutaneous growths. Last week I was mistaken for being in my 40s, 20 years younger than reality. Of course this could be many other things: genes, healthy lifestyle, other interventions, who knows. In any case, so far there are no obvious negatives. But we shouldn't kid ourselves: we are being lab rats.

 

[Phil Goodman]

We're largely on our own with this. There's this frequent argument that we should take breaks, but it seems to be based more on speculation and caution than anything concrete. Assuming copper intake is reasonable, my hope is that as with testosterone, the short half-life and pulsatile delivery of modest amounts will yield benefits with minimal disruption of the endogenous systems.

For what it's worth, I've been injecting 1 mg six times a day for several years. Regarding possible correlations, I perceive improvements in skin quality and the disappearance of some presumably benign subcutaneous growths. Last week I was mistaken for being in my 40s, 20 years younger than reality. Of course this could be many other things: genes, healthy lifestyle, other interventions, who knows. In any case, so far there are no obvious negatives. But we shouldn't kid ourselves: we are being lab rats.

Good to know. I’ve always been hesitant to dive in too deep with peptides, and just stick with ghk cu and bpc, usually two rounds of each per year…. so only a total of about 10-12 weeks of each one annually. Like you said, we’re all lab rats so it’s promising to hear you’ve been running such high dosages for extended periods of time with no issues. Out of curiosity, where do you get your peptides? I’ve always gone with Peptide Science due to being put together in the US and also lots of lab testing to confirm quality. The price is a little steep though, so if there are other places to get high quality peptides at a better price that would be helpful.

 

[Cataceous]

... Out of curiosity, where do you get your peptides? I’ve always gone with Peptide Science due to being put together in the US and also lots of lab testing to confirm quality. The price is a little steep though, so if there are other places to get high quality peptides at a better price that would be helpful.

I agree that Peptide Sciences is considered the most trustworthy, though ironically I have had a couple of QC issues with them. I also use Nootropic Source because they have a good price on GHK-Cu in quantity. However, I have not done any independent testing to quantify things.