Genomic Insights into PCOS: Causal Mechanisms & Classifications

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Keynote lecture on: Deconstructing a Syndrome – Genomic Insights into PCOS Causal Mechanisms and Classification Speaker: Andrea Dunaif, Icahn School of Medicine at Mount Sinai, USA

 

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Thread 'Initiative Calls for Updated Standards in Testing for Suspected Low Testosterone'

Apr 4, 2025

* Dr. Dunaif was a featured speaker at this CDC meeting. “We hope that the CDC initiative will finally lead to accurate testosterone measurements by clinical laboratories almost 20 years after the Endocrine Society position statement. It is exceptionally disappointing that major clinical laboratories have ignored the Endocrine Society and CDC recommendations. Health care provider education on the correct testosterone assay methodology will be critical for ensuring that clinical laboratories clearly indicate the correct assay methodology in their test ordering options,”...

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• cdc hypogonadism pcos Standardized T-assays
• Replies: 12
• Forum: Testosterone and Men's Health Articles

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Thread 'Groundbreaking Study Links DNA Variants to Testosterone Overproduction in PCOS'

Sep 1, 2025

Dr. Dunaif

* For the first time, we have shown how specific inherited DNA variants in PCOS change gene activity and increase testosterone production. That moves us from statistical association to biological mechanism.

Research could pave way for new therapies to treat polycystic ovary syndrome​

Mount Sinai-Duke University Study Identifies DNA Variants That Increase Testosterone Production in PCOS Patients | Mount Sinai - New York

www.mountsinai.org

Journal: Nature Communications...

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• dna gene dennd1a pcos testosterone
• Replies: 6
• Forum: HRT in Women

 

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Thread 'Heart Disease Risks in Women with PCOS: New Insights, Therapies, and Gaps in Research'

Sep 1, 2025

In this webinar, Dr. Licy Yanes Cardozo presents the heightened cardiovascular risks in women with PCOS, the mechanisms underlying these risks, current treatments available, potential new therapies, and the existing knowledge gaps in women's health research.




Summary

Complications of Androgen Excess in women

Summary II

EXCESS OF ANDROGENS IN WOMEN

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• cvd Diagnosis/tretments pcos testosterone
• Replies: 2
• Forum: HRT in Women

 

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Thread 'Polyendocrine metabolic ovarian syndrome, the new name for polycystic ovary syndrome'

Jul 6, 2026

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• androgens health pcos treatment
• Replies: 3
• Forum: HRT in Women

 

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Thread 'Laboratory Evaluation in PCOS/PMOS: Improving Accuracy, Interpretation, and Standardization'

Aug 16, 2026

* Shalender Bhasin, MD, is a Professor of Medicine at Harvard Medical School, Director of the Boston Claude D. Pepper Aging Research Center, and Director of the Center for Clinical Investigation at Brigham and Women’s Hospital. He is an internationally recognized expert in testosterone biology and has conducted many of the most important randomized controlled trials of testosterone in men and women. His laboratory has characterized the mechanisms of testosterone’s action, including the role of steroid 5-alpha reductase in adults....

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• Assays Evaluation health Pcos/pmos testosterone
• Replies: 1
• Forum: HRT in Women