Free Test & Estradiol Questions

[modawg2k]

On TRT for over 2 months and just received my first Free Test and Estradiol. I assumed my Estradiol would be high based off how crappy I started to feel about 1.5 months into treatment. A few questions:

Testosterone, Total, LC/MS/MS – 649 (250 - 1100 ng/dL)
Testosterone, Free - 103.5 (35 - 155 pg/mL)
Estradiol - 53 H (7-50 pg/mL)

1) How do I evaluate my Free T? The forum states 2% but not sure how to figure that out with my labs.
2) For estradiol, I don't see anything about this lab being the sensitive, so did I get the wrong one?
3) What are ways to decrease Estradiol without having to take an AI?
4) If an AI is called for, what would be a good starting dose of anastrazole?

 

[Vince]

Your free T is in a good range, nothing to be concerned with. I wouldn't start an AI without the right estradiol test, you had the wrong one. Sensitive E LC/MS/MS test

 

[modawg2k]

Is your peak Estradiol level generally on your Testosterone trough day, or are those two not related?

 

[Vince]

I always get labs done on my trough day. Remember estradiol follows T, so on days your T is higher your E2 will be higher.

 

[FeelingLost]

On TRT for over 2 months and just received my first Free Test and Estradiol. I assumed my Estradiol would be high based off how crappy I started to feel about 1.5 months into treatment. A few questions:

Testosterone, Total, LC/MS/MS – 649 (250 - 1100 ng/dL)
Testosterone, Free - 103.5 (35 - 155 pg/mL)
Estradiol - 53 H (7-50 pg/mL)

1) How do I evaluate my Free T? The forum states 2% but not sure how to figure that out with my labs.
2) For estradiol, I don't see anything about this lab being the sensitive, so did I get the wrong one?
3) What are ways to decrease Estradiol without having to take an AI?
4) If an AI is called for, what would be a good starting dose of anastrazole?

1) Testosterone, Free - 103.5 (35 - 155 pg/mL) is 10.35 ng/dL
2% of TT649 is 12.98ng/dL

2) probably so

3) First and foremost lose the belly fat then take zinc, Mag, grapeseed, eat cruciferous veggies every day raw or steamed don't over cook, no plastic bottles, no tupperware in the microwave, Research how to avoid BPA's and Xenoestrogens.

4) .125 EOD

hth

 

[modawg2k]

1) Testosterone, Free - 103.5 (35 - 155 pg/mL) is 10.35 ng/dL
2% of TT649 is 12.98ng/dL

Correct me if I'm wrong, but doesn't 103.5pg convert to 0.1035 ng? So I can't use that 2% marker unless I missing something here.
Also, for #4) 0.125 EOD, so are you cutting a 1mg tab into 1/8ths to get that small of a dose?

 

[FeelingLost]

Correct me if I'm wrong, but doesn't 103.5pg convert to 0.1035 ng? So I can't use that 2% marker unless I missing something here.
Also, for #4) 0.125 EOD, so are you cutting a 1mg tab into 1/8ths to get that small of a dose?

Google is loaded with pg to ng converters I used this one:
http://www.endmemo.com/sconvert/pg_mlng_dl.php
#4) No I have a prescription with .125mg pills.

 

[madman]

Correct me if I'm wrong, but doesn't 103.5pg convert to 0.1035 ng? So I can't use that 2% marker unless I missing something here.
Also, for #4) 0.125 EOD, so are you cutting a 1mg tab into 1/8ths to get that small of a dose?

https://www.nebido.com/en/hcp/research/testosterone-tools/free-calculator.php fill in your shbg/total testosterone values.

 

[modawg2k]

Google is loaded with pg to ng converters I used this one:
http://www.endmemo.com/sconvert/pg_mlng_dl.php
#4) No I have a prescription with .125mg pills.

I was scratching my head thinking you are crazy with your calculation.... but then I realized that the Total T was in dL and not mL.... Thanks for the link. And I see your AI is compounded to get that strength for you, thanks for the pic of it.

 

[modawg2k]

https://www.nebido.com/en/hcp/research/testosterone-tools/free-calculator.php fill in your shbg/total testosterone values.

SHBG is something I have not gotten tested for yet, but I know I should based off the feedback from this site. I meet with my PCP to discuss this week and I may need to ask specifically for it. What are the reasons I need it so that I can make sure I have a thorough conversation? Thanks

 

[modawg2k]

I always get labs done on my trough day. Remember estradiol follows T, so on days your T is higher your E2 will be higher.

And this is why it's better to inject more frequently with less dose/injection?