Finally Making the switch from Clomid to Enclomiphene

Mfri225 · Apr 6, 2025

Hey guys just wanted to update you on my clomid journey. For 2 years I was on clomid, my numbers were pretty dang good and I responded well. Check out my other posts more detail there. Up until this year tho I did start to feel kinda off. My sex drive was always really good but my mood was off and the anxiety was becoming too much. It was frustrating because I felt good in some areas but not so good in others. I am 27 years old, I do not want to start TRT right now. I recently finally made the switch to enclomiphene. I was taking 100 mgs weekly of clomid before I started the enclo. Right now I am on week 2 of the enclo taking 12.5 mg everyday and I am feeling a bit better. I was finally able to find a good compounding pharmacy and I did not want to go the research chem route even tho some of them are probably decent sources. Do you find it makes a difference taking the enclo on a empty stomach versus with a meal? I have been experimenting with both. I would love to hear your experience on enclo. I will circle back with updated labs with the next 8 weeks or so. My mood is a lot better that is the one thing I have noticed so far. I know it takes time for the zooclomiphene to clear the system. I did not cycle off I just jumped straight to enclomiphene.

aj allday · Sep 30, 2025

Mfri225 said:
Hey guys just wanted to update you on my clomid journey. For 2 years I was on clomid, my numbers were pretty dang good and I responded well. Check out my other posts more detail there. Up until this year tho I did start to feel kinda off. My sex drive was always really good but my mood was off and the anxiety was becoming too much. It was frustrating because I felt good in some areas but not so good in others. I am 27 years old, I do not want to start TRT right now. I recently finally made the switch to enclomiphene. I was taking 100 mgs weekly of clomid before I started the enclo. Right now I am on week 2 of the enclo taking 12.5 mg everyday and I am feeling a bit better. I was finally able to find a good compounding pharmacy and I did not want to go the research chem route even tho some of them are probably decent sources. Do you find it makes a difference taking the enclo on a empty stomach versus with a meal? I have been experimenting with both. I would love to hear your experience on enclo. I will circle back with updated labs with the next 8 weeks or so. My mood is a lot better that is the one thing I have noticed so far. I know it takes time for the zooclomiphene to clear the system. I did not cycle off I just jumped straight to enclomiphene.

Any updates on how the enclo worked out for you?

Mfri225 · Sep 30, 2025

aj allday said:
Any updates on how the enclo worked out for you?

Its been good. My mood is more stable. I was on 12.5 ed for 9 weeks and it was almost too much. Brought me to 1300 total t. My hematocrit creeped up a bit too around 51.1% so I lowered my dosage to 12.5 4 days a week. I just got my labs done so curious to see if there is a drastic difference. Anxiety has been super high and its frustrating. I think I am just hypersensitive to caffeine now which sucks because I love coffee. My DHEA is a bit low so I am curious if I supplement with that to maybe offset some anxiety. Overall things are more stable on enclomiphene.