Estradiol, sensitive less than 20

ipi I have low E-2 as well. 13 Ultra sensitive and it still moved very little while I was on TRT.
My T at one point was at a 1000 and my E-2 moved to around 16 whereas some guys go off the chart.
It's tricky for some of us but I like the idea of a lower value and not have to take an A.I. as some do.
As for the aches and pains-the TRT orked like magic for me.
Since I have been off pending some issues the pains are back plus some :(
 
Joe

What kind a pains you had? I am on s 0.8 TRT Once weekly. I am in a great pain. How long does it take, I just had my first injection.
 
Joe

What kind a pains you had? I am on s 0.8 TRT Once weekly. I am in a great pain. How long does it take, I just had my first injection.

These are joint pains you are experiencing? If so, and presuming they are the result of the very low estradiol levels you presented with, then testosterone may well provide some relief. As testosterone rises, estradiol typically rises. That said, it's not an overnight process. One of the elements to a successful TRT protocol is patience.
 
ipi sorry for the slow reply.
I have degenerative disc in the neck and low back and arthritis which causes ma a lot of pain.
When on TRT i had much less pain.
In response to other causes of pain and mood I just found out that my serum calcium is high which can be an indicator of parathyroid malfunction. After reviewing old blood work I see that it has been close for several years with borderline high serum calcium.
I was on .7 T weekly for about a year. Just filled new script and getting ready to try again.
It can cause an array of problems as well from joint pain to Erectile Dysfunction.
I find this interesting as I had ED come out of nowhere.
So check all of the bases as you go and good luck.
 
ipi sorry for the slow reply.
I have degenerative disc in the neck and low back and arthritis which causes ma a lot of pain.
When on TRT i had much less pain.
In response to other causes of pain and mood I just found out that my serum calcium is high which can be an indicator of parathyroid malfunction. After reviewing old blood work I see that it has been close for several years with borderline high serum calcium.
I was on .7 T weekly for about a year. Just filled new script and getting ready to try again.
It can cause an array of problems as well from joint pain to Erectile Dysfunction.
I find this interesting as I had ED come out of nowhere.
So check all of the bases as you go and good luck.

Gluten, a protein in wheat , may cause a flare up of arthritis symptions, according to the arthritis foundation. I've been grain-free for almost five years now.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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