Estradiol - How Long to Recover After a Crash?

Corwin1968

New Member
I just started a protocol of 50mg T M-W-F, 300iu HCG M-W-F and .25mg Anastrazole M-W-F.

My starting total T was 1200, Free T was 31 and Estradiol was 45. This was on 250mg T per week and 1mg of Anastrazole per week.

My first few days on the new protocol I could feel that I was starting to improve, both in mental outlook and libido. In the last couple of days, the libido has fallen off but mood has stayed pretty good, except this morning I found myself getting really irritable.

I'm thinking it's possible that I've crashed my Estradiol levels since my TRT was reduced by 100mg but the Anastrazole was only reduced by .25mg. In no way was my previous protocol dialed in so the 250 T and 1mg Anastrazole don't necessarily represent an optimal schedule.

How fast or slow can I expect to feel a change in Estradiol levels? I skipped the Anastrazole today but I don't know how quickly I might feel a difference. I have very high body fat so I likely convert a larger percentage of my T than the average sized guy.
 
If it were me I'd stop the ai at that dose and check bloodwork. Odds are in favor of not needing it.

You T dose was a little high but e2 barely out of range. Of course that's Day 7.
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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