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Vince

Super Moderator
Thanks Vince. I was wondering, can you educate me a bit on the difference between Levothyroxine and other possible preparations?

I was quite surprised to see the following on Levothyroxine:

"Levothyroxine is synthetic thyroxine (T4). Due to its prolonged half-life, levothyroxine steady-state concentrations are not achieved until ~6 weeks after therapy is initiated or dosage adjustment".
You adjust your dose of T3 and T4 by your labs. I am currently taking 90 MG of armor and 6.25 MCG of generic cytomel twice daily.
 
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trtthings

Active Member
Armor once a day cytomel twice a day.
How did you decide Armor and cytomel was for you, as opposed to Levothyroxine monotherapy?

I am curious to try T3 along with the T4 but as you're probably well aware of it is hotly debated whether T3 is beneficial in any way. Where I'm from Levothyroxine (and equivalent) is pretty much the only thing they offer. It is possible to prescribe T3 with an exception but the doctor is then risking being branded as somebody who practices "fake medicine".

If my understanding is correct, Armor's ratio of T3:T4 is also far greater than what is found in humans (it's the pig one, right?).

In any case I will probably push for cytomel (or equivalent) using this as the argument: UpToDate

It might be enough of a defence for my GP if they come for him for it. The doses used for these scenarios are 25 - 50mcg daily.
 

Vince

Super Moderator
How did you decide Armor and cytomel was for you, as opposed to Levothyroxine monotherapy?

I am curious to try T3 along with the T4 but as you're probably well aware of it is hotly debated whether T3 is beneficial in any way. Where I'm from Levothyroxine (and equivalent) is pretty much the only thing they offer. It is possible to prescribe T3 with an exception but the doctor is then risking being branded as somebody who practices "fake medicine".

If my understanding is correct, Armor's ratio of T3:T4 is also far greater than what is found in humans (it's the pig one, right?).

In any case I will probably push for cytomel (or equivalent) using this as the argument: UpToDate

It might be enough of a defence for my GP if they come for him for it. The doses used for these scenarios are 25 - 50mcg daily.
I have high reverse T3, the only way I can lower it. Is by supplementing T3. It helps all my levels. I do better, with my free T4 levels are lower. When I have higher free T4 levels I convert more into reverse T3.

I’d buy tiromel 25mcg (T3) from India. It’s very easy to cut into quarters, that’s why I buy it. The cost is $42 for 100 tablets. Very reasonable.
 

trtthings

Active Member
I have high reverse T3, the only way I can lower it. Is by supplementing T3. It helps all my levels. I do better, with my free T4 levels are lower. When I have higher free T4 levels I convert more into reverse T3.

I’d buy tiromel 25mcg (T3) from India. It’s very easy to cut into quarters, that’s why I buy it. The cost is $42 for 100 tablets. Very reasonable.

That's really interesting to hear. We don't have a single lab in my country that measures rT3. So taking T4 almost harms you more than it helps you (?).

I will definitely try to get the T3 prescription, I need to see if it helps. My GP is very conventional though.
 

Vince

Super Moderator
That's really interesting to hear. We don't have a single lab in my country that measures rT3. So taking T4 almost harms you more than it helps you (?).

I will definitely try to get the T3 prescription, I need to see if it helps. My GP is very conventional though.
You definitely need some T4 in your body, otherwise you could crash. And have nothing. That’s why you need both T4 and T3. You may not convert enough T4 into free T3. And you could convert too much the T4 into reverse T3, like me. So you need both types of meds. If you’re not allowed to check reverse T3. Then just use the labs you can get.
 

Vince

Super Moderator
That's really interesting to hear. We don't have a single lab in my country that measures rT3. So taking T4 almost harms you more than it helps you (?).

I will definitely try to get the T3 prescription, I need to see if it helps. My GP is very conventional though.
 

trtthings

Active Member
Levothyroxine, all the symptoms of Hypo.

Sorry I dont have anything to add, I was venting.
All of them?

* Sensitivity to cold
* Fatigue
* Low libido
* Weight gain
* Reduced blood flow (??)
* Dry skin
* Depression
* Slow thinking / movemens
* Weakness

(I wonder if there are more).

What else? Why did you start TRT/are you still on it?
 

trtthings

Active Member
@Vince

Two last questions:

1. What happens when you go too high with T4 and get too much rT3, just a return of the initial hypo symptoms?

2. Is T3 as poorly absorbed as T4? When you take it in the afternoon, does it have to be some time after/before a meal?
 

Vince

Super Moderator
@Vince

Two last questions:

1. What happens when you go too high with T4 and get too much rT3, just a return of the initial hypo symptoms?

2. Is T3 as poorly absorbed as T4? When you take it in the afternoon, does it have to be some time after/before a meal?
Your first question, I would answer yes.

I try to take my second dose of T3, 12 hours apart for my first dose. I do take it on an empty stomach, about 2 to 3 hours after a small meal. I stick it up underneath my gum and let it absorb or break down. I try not to eat or drink anything, except water. For one hour. Yes it can be a pain but I try to follow the guidelines.
 

Goldilox

New Member
So my experience so far with TRT has been that morning wood is non-existent without anastrozole, and I can make it appear like clockwork when taking it.

However for the past week or so I've been having trouble with erection quality and duration (when using it). Does anyone have any insight on what might be going on?

So far my thoughts are:
* Too high E2
* Too low E2
* Too low PRL? It was lower than usual on a recent blood test
* Blood pressure rising due to TRT and salt intake? (I haven't measured nor do I have a solid baseline)

And what do you guys use to combat this, if anything? Cialis?
71D75F35-E294-40C9-BA7F-8453347F086F.jpeg
 
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