Enclomiphene dose

I had at one point taken clomid 50mg 3x a week to resutls in 1000ng total test and above reference range free test. I had to stop due to eye floaters.

Now i bought some enclomiphene and wonder what dose I should start with. Technically if clomid is a 50/50 isomer, then 25mg 3x a week would be similar? However, enclo has a much shorter half life, so many 12.5mg EOD would be similar?
 
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I had at one point taken clomid 50mg 3x a week to resutls in 1000ng total test and above reference range free test. I had to stop due to eye floaters.

Now i bought some clomid and wonder what dose I should start with. Technically if clomid is a 50/50 isomer, then 25mg 3x a week would be similar? However, enclo has a much shorter half life, so many 12.5mg EOD would be similar?
Hey!

So you wanna try Clomid again, but with a lower dose to avoid eye floaters. You're thinking 25mg 3x a week or 12.5mg EOD, considering the isomer and half-life.

Honestly, it's best to consult a doc for personalized advice. But if you do decide to start again, start low and monitor your test levels. And if you experience any side effects, stop and consult a doc.
 
Hey!

So you wanna try Clomid again, but with a lower dose to avoid eye floaters. You're thinking 25mg 3x a week or 12.5mg EOD, considering the isomer and half-life.

Honestly, it's best to consult a doc for personalized advice. But if you do decide to start again, start low and monitor your test levels. And if you experience any side effects, stop and consult a doc.
sorry, i edited my post. I switched to enclomiphene now and trying to figure out an equivalent dose.
 
You logic sounds reasonable, however there may be other variables involved. For example, if Zuclomiphene and Encomiphen compete for the same receptors, then removing Zuclomiphene could make the same dose of Enclomiphene effectively a higher dose. Hence, starting at a lower dose and working up if necessary seems more appropriate. As with every other dosing decision, experimentation, starting low and working up, is almost always the answer.

BTW, I think you replied to a bot.
 
Until I went with 25mg enclo ED, nothing less moved the needle to optimize androgen levels. But I wonder if my floaters increased despite the lack of reports that enclo causes them unlike clomid. Just getting rid of the estrogenic isomer (zuclo) should be safe enough.
 

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Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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