Effects of selective serotonin reuptake inhibitors on endocrine system

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Effects of selective serotonin reuptake inhibitors on endocrine system (Review) - PMC

Selective serotonin reuptake inhibitors (SSRIs) are typically prescribed for treating major depressive disorder (MDD) due to their high efficacy. These drugs function by inhibiting the reuptake of serotonin [also termed 5-hydroxytryptamine (5-HT)], ...

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The six most widely used selective serotonin reuptake inhibitors decrease androgens and increase estrogens in the H295R cell line - PubMed

Selective serotonin reuptake inhibitors (SSRIs) used as first line of treatment in major depressive disorder (MDD) are known to exert negative effects on the endocrine system and fertility. The aim of the present study was to investigate the possible endocrine disrupting effect of six SSRIs...

pubmed.ncbi.nlm.nih.gov