Did anyone in particular at Defy make that statement about progesterone? I'd like to know the reasoning. I have discussed my supplementation with Jill, and it sounded like they'd have no objections to prescribing it.
Defy... Do not replace progesterone in men. Kind of confused. If there is a real Progesterone deficiency in a man, why not supplement with Progesterone Bioidentica?
Dr Calkins told me that they do not like to use progesterone directly in men and the reasoning was because its easy to overshoot the mark and can cause more issues than its worth.
I started out taking six times my current dose of progesterone, titrating down to put serum levels at mid-range. I didn't encounter any obvious problems with this. It makes little sense to me to try raising it indirectly with massive doses of pregnenolone. Even relatively small doses of pregnenolone caused me issues with anxiety.
Do you have a recommended starting dose for progesterone cream if I wanted to start it on the low end?
Five milligrams is on the lower end for a transdermal. If absorption is about 10% then this is giving you less than the 600 mcg I'm injecting. With nighttime dosing I'm at mid-range serum levels in the morning.
I agree. My SHBG, Dhea and progesterone are low. The normal E2 with a tendency to increase. I need to make my testicles grow back and the amount of sperm too. So I'm in doubt to use 250 Ui of HCG twice a week and increase E2 too much. And progesterone I thought of using 2Mg pentravan transdermal gel and supplementation with 50 mg of Dhea. What do you think? I have to go slow because I tend to Prostatic Hyperplasia at 51 years old.
Is this gel the high absorption pentravan transdermal?
That seems like a conservative dose of progesterone, depending on absorption. But 50 mg of DHEA is a lot. I'd try 12.5 or 25 mg first to see where that puts serum DHEA-S levels.
I'm not sure which cream-based product @antelopers is thinking about. I've tried progesterone in oil with satisfactory results, but I prefer injections.
OK thank you. I ended up buying the 100Mg Dhea. Could you take 100Mg every 2 days? I don't know much about Dhea supplementation. I only see the gym people taking 100Mg a day but it can really be a high dose for me.
Or get a pill splitter to make more reasonable doses out of them, unless it's capsules.
Yes. It is in capsule.
It's possible to perform a "dry" dilution by mixing contents with cornstarch, but maybe not worth the trouble.
I thought about removing the contents of the capsule and dividing. I put it in the water and drank. But I don't know if it would work because of absorption.
That probably works fine. The doses may be imprecise, but that shouldn't matter much as long as you're averaging the desired amount.
Yes. I will test to see. Thanks
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