Effect of aerobic exercise on erectile function

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madman

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Abstract

Background:
The health benefits of regular aerobic exercise are well established, although there is limited high-quality evidence regarding its impact on erectile function.

Aim: To determine the effect of aerobic exercise on erectile function in men and to identify factors that may influence this effect.

Methods: This systematic review and meta-analysis included randomized controlled trials that evaluated the effects of aerobic exercise on erectile function via the Erectile Function domain of the International Index of Erectile Function (IIEF-EF). The mean difference in IIEF-EF scores between the aerobic exercise and nonexercising control groups was estimated by a random-effects meta-analysis. Meta-regression was used to evaluate the association of moderator variables on meta-analysis results.

Outcomes: The IIEF-EF score is reported on a 6-30 scale, with higher values indicating better erectile function.

Results: Among 11 randomized controlled trials included in the analysis, aerobic exercise resulted in statistically significant improvements in IIEFEF scores as compared with controls, with a mean difference of 2.8 points (95% CI, 1.7-3.9; P < .001) and moderate heterogeneity among studies(I2 = 53%). The effect of aerobic exercise on erectile function was greater in men with lower baseline IIEF-EF scores, with improvements of 2.3,3.3, and 4.9 points for mild, moderate, and severe erectile dysfunction, respectively (P = .02). The meta-analysis results were not influenced by publication bias or individual study effects.

Clinical Implications: Healthcare providers should consider recommending regular aerobic exercise as a low-risk nonpharmacologic therapy for men experiencing erectile difficulties.

Strengths and Limitations: The primary strength of this review was the generation of level 1 evidence on a topic of general interest regarding sexual health in men. However, the included studies evaluated diverse groups, which may complicate data interpretation for specific segments of the population.

Conclusion: Regular aerobic exercise can improve the erectile function of men, particularly those with lower baseline IIEF-EF scores.




Conclusion

Regular aerobic exercise can improve the erectile function of men, particularly those with lower baseline IIEF scores, and it can be considered a low-risk and effective nonpharmacologic therapy for men at risk of or currently experiencing ED. Future RCTs should explore optimal exercise regimens to support the development of prescriptive guidelines for improving erectile function.
 

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*The researchers involved in the trials found that those volunteers who participated in the exercise regimens saw a 5-point improvement in erectile function. They also found that the more severe the condition, the greater the improvement. The researchers also noted that volunteers given Viagra or Cialis saw improvements of 4 to 8 points, while those given testosterone saw improvements of just 2 points.
 

*The male sexual response cycle is complex and the exact role of testosterone in mediating libido, arousal, erection, ejaculation, and orgasm is multifactorial

*This hormone isn’t the only biological factor with clear, substantial power over our libidos
 

*Testosterone replacement therapy can improve several aspects of sexual life, including erection, only in hypogonadal subjects but its contribution alone is clinically effective only in milder forms of erectile dysfunction





*Clinically, the optimal population of men with ED who will benefit most from TRT is unclear. There were inconsistent results on the impact of age on treatment efficacy and while multiple RCTs have focused on just older men, a parallel large study on younger men is still lacking. The threshold of ED and T deficiency severity for which TRT is efficacious, the dosing of TRT, the timing for initiating combination therapy, and the duration of the treatment have yet to be outlined in clinical guidelines. Presumably, TRT monotherapy could be first-line for patients with severe T deficiency but milder forms of ED (with PDE5i as salvage therapy if the response is poor), whereas combination TRT and PDE5i would be first-line for those with severe T deficiency and severe ED.





*It is important to recognize that, whatever outcome is considered, the effects of TRT are clearly evident only in the presence of hypogonadal status (ie, total T < 12 nmol/L), whereas the positive effects of TRT are no longer confirmed for higher T levels. In addition, TRT alone can be effective in restoring only milder forms of ED, whereas combined therapy with other drugs is required when more severe vascular damage is present
 
Beyond Testosterone Book by Nelson Vergel
IME cardio conditioning is very under-rated for promoting EQ. It's unfortunate that the training methods used in the study above were not included as I suspect HIIT is even more effective and likely more appealing for most people than the endless repetition implied by "aerobic" training.
 
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