E2 Sweetspot - Larger Erection Than Normal?

Not sure honestly. Haven’t really seen many people experiment and try to raise low SHBG by improving their insulin sensitivity. Do u know where u sit insulin resistance wise?

What’s the best way to test for insulin resistance? Just test fasting insulin levels? Or do u look at insulin levels, A1C and fasting glucose levels, and make an assessment based on all 3?
Dr. Perlmutter stated that the truest measurement for blood glucose monitoring was A1C. I don’t have any measurements lately, but my fasting glucose was elevated while taking Ibutamoren. High fasting blood glucose isn’t normal for me otherwise.
 
As my estrogen approach ~60-70 pg/mL, my erections are as full as possible. When I knock estrogen down to 30-40 pg/mL, my erections are much softer and it is much harder to orgasm. Estrogen plays a critical role in erectile function.
That’s interesting. I’ve recently been taking raloxifene for a small gyno lump I’ve developed over the years. First thing I notice was a drop in erection quality. I figured it was the serms agonist activity on the ER in the penis, but maybe it is it’s antagonist in the penis instead
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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