Dr Simon Reviews the Most Important Advances in Menopause 2024

madman

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In this informative video, Dr. James Simon, a renowned expert in women's health, discusses significant advancements in menopause management as of 2024. He highlights four notable publications from 2024 that delve into the latest research on menopause, providing valuable insights for both patients and healthcare providers.




Dr. Simon also reviews three pivotal studies:

Menopausal Hormone Therapy and Cardiovascular Risk:
A comprehensive study involving 900,000 Swedish women concluded that hormone therapy (HT) does not significantly alter cardiovascular risk.

Systematic Review and Meta-Analysis on HT and Cognition: This analysis found that while HT had no significant cognitive effects during midlife, it was associated with improved verbal memory in later life.

KEEPS Study on Long-Term Cognitive Effects of HT: The study determined that initiating HT during early menopause does not have long-term cognitive benefits.




Furthermore, Dr. Simon discusses four additional papers focusing on HT in menopausal and postmenopausal women, all of which affirm the safety of hormone therapy.

He concludes by outlining the benefits of HT for postmenopausal women aged 65 and older, as well as for breast cancer survivors, emphasizing the positive outcomes associated with hormone replacement therapy.





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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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