Sexual Function, Mood and Drive. DHT and E2.

CRASH TEST DUMMY SIGNING IN..
O.K.
My unscientific, scientific test with N-1 Crash Test Dummy
Here is the before scrotal application AND after scrotal application.
2 CLICKS (100mg compounded cream from Empower)
Ranges are above.
Test date.........1-16-19 VS 2-7-19
DHEA.............,,,,,,,,,,,,...15 VS 32
TEST, FREE......,,,,,,,,,,.136 VS 404
TEST, TOTAL (MS)..933 VS 1644
SHGB............................41 VS 41
DHT..............................460 VS 430
E2 - ULTRA SENS....59 VS 119
Based on above I added in a little AI (0.07mg) 3 days a week.
I might drop down to 1 CLICK a day and see what those results are......
I will start back on 25 mg of DHEA also....

I am surprised DHT didn't go up.
 
Very true, but I’ve been bald for 20 years so... The prostate could be an issue. However, there is a lot of misinformation surrounding prostate issues.

Everything I have read about DHT is that higher DHT doesn't cause prostate growth, while low DHT can cause the prostate to shrink. And that serum levels of DHT don't relate to tissue (prostate) levels.
 
From reading a lot of protocols, it seems to be there are multiple ways to get dialed in. Likely more than one way to achieve the same goal even in the same individual.
 
Anyone have experience running just nandrolone (deca) with HCG? My understanding is that nandrolone works directly on the androgen receptors with essentially no aromatisation. Drawback is a near total shutdown of endogenous testosterone production.....So HCG would need to be added. Can this be sustained over the long-term? Forgive my ignorance - I am still relatively new to hrt.... about 6 months in and trying to get everything dialed still.
 
CRASH TEST DUMMY SIGNING IN..
O.K.
My unscientific, scientific test with N-1 Crash Test Dummy
Here is the before scrotal application AND after scrotal application.
2 CLICKS (100mg compounded cream from Empower)
Ranges are above.
Test date.........1-16-19 VS 2-7-19
DHEA.............,,,,,,,,,,,,...15 VS 32
TEST, FREE......,,,,,,,,,,.136 VS 404
TEST, TOTAL (MS)..933 VS 1644
SHGB............................41 VS 41
DHT..............................460 VS 430
E2 - ULTRA SENS....59 VS 119
Based on above I added in a little AI (0.07mg) 3 days a week.
I might drop down to 1 CLICK a day and see what those results are......
I will start back on 25 mg of DHEA also....

Interesting results on your "CTD" experiments!
Hope you're feeling well on it - you don't say too much about subjective results, though I assume adding the AI means you had symptoms from the large rise in E2.

It will be interesting to see how you do with your plan to halve the dose to 1 Click, 50mg, applied scrotally. Assuming you maintain adequate levels of FT it should hopefully work well for you.
 
Last edited:

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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