Dhea/dim

DHEA does cause my estradiol levels to rise. Not enough to add an AI.
I just supplement with DHEA to keep my levels in the high range, for any health benefits.
 
Vince-do you know how many points it causes you're E2 to rise?

There's no way to say, none of it is linear. DHEA in certain forms like cheap OTC tablets are particularly bad, creams are better, micronized capsules are very good, even sublingual delivery is better, but DHEA is a notorious converter in men, not every man though.

DIM is widely panned, some guys thinks its good though, will not hurt you to try 200mg/D but an estrogen blocker it is NOT.
 
DIM may have a modest impact, but by no means is it an AI/estrogen blocker. If it was, far fewer prescriptions for anastrozole would be written.
 
When taking DHEA is it recommended to take an estrogen blocker like DIM? I'm taking 40 mg oh DHEA every night.

Why 40mg? Most men, 25mg will get DHEA-s in the range you want. I have not seen real world effectiveness of DIM, but typical doses used by men as HRT, 25-50mg, should not require an AI.
 
Vince-do you know how many points it causes you're E2 to rise?

I don't remember the amount but it definitely did lower my testosterone and raise my estradiol levels. I tried it twice and both times it did lower my testosterone and raise my estradiol.
 
I thought the rule of thumb was to wait and see if your E2 becomes a problem. Taking an AI because you assume it raises E2 doesn't make a lot of sense.
 
If DIM wouldn´t work I wonder why Dr Crisler suggests DIM+CDG

It's what guys want to hear and some even expect and may even question their DRs when these things are not "prescribed", but beliefs vary on these things being effective at doing more than litening one's wallet. By and large those two things aren't really well regarded on this forum, CDG has a slightly better rep than DIM which is widely panned as doing anything.
 
I taked them both for a while but if they are not very effective I rather skip them. I want to reduce my supplements because its already crazy what I spend per month on different supplements. Multivit., B-vit forte, K1, Vit D, Omega 3, Old garlic (Kyolic), Q10, Magnesium, Selenium, ALC, DHEA, Preg, Vit C 1000mg, NAC, Zinc and L-Citrl. Since Im on statins I do need to take Q10, Selelium and K1. If I don´t take multivit I take the rest individually. Man, the drawer is full and my wife thinks I´m obsessed and I think I´m lol
 
I taked them both for a while but if they are not very effective I rather skip them. I want to reduce my supplements because its already crazy what I spend per month on different supplements. Multivit., B-vit forte, K1, Vit D, Omega 3, Old garlic (Kyolic), Q10, Magnesium, Selenium, ALC, DHEA, Preg, Vit C 1000mg, NAC, Zinc and L-Citrl. Since Im on statins I do need to take Q10, Selelium and K1. If I don´t take multivit I take the rest individually. Man, the drawer is full and my wife thinks I´m obsessed and I think I´m lol
LOL..I'm right with you brother, I'm also obsessed with all the supplement.
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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