sportsfan8724
Member
Has anyone increased their dht using creatine monohydrate?
Creatine monohydrate
- Thread starter sportsfan8724
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Vince Carter
Banned
I never tested DHT on it but I never felt anything that I could tell. I like the supplement and used it "correctly", dose and timing, but you'd probably have to undergo repeated testing while using it. I eventually went w a cream on the scrotum to encourage DHT production, that was an addition to my injections of Cyp.
CoastWatcher
Moderator
https://www.excelmale.com/forum/sho...ne-and-water-retention&highlight=Creatine+DHT
Please scroll down to post nine of this thread. Nelson cites a study that indicates creatine can impact DHT (this may be the small study ERO referenced).
Please scroll down to post nine of this thread. Nelson cites a study that indicates creatine can impact DHT (this may be the small study ERO referenced).
[FONT="]The following double-blind placebo-controlled study at the Stellenbosch University South Africa might be an interesting read. [/FONT]
[FONT="]
Three weeks of creatine monohydrate supplementation affects dihydrotestosterone to testosterone ratio in college-aged rugby players.
[/FONT]
[h=3]Abstract[/b][h=4]OBJECTIVE:[/b]This study investigated resting concentrations of selected androgens after 3 weeks of creatine supplementation in male rugby players. It was hypothesized that the ratio of dihydrotestosterone (DHT, a biologically more active androgen) to testosterone (T) would change with creatine supplementation.
[h=4]DESIGN:[/b]Double-blind placebo-controlled crossover study with a 6-week washout period.
[h=4]SETTING:[/b]Rugby Institute in South Africa.
[h=4]PARTICIPANTS:[/b]College-aged rugby players (n = 20) volunteered for the study, which took place during the competitive season.
[h=4]INTERVENTIONS:[/b]Subjects loaded with creatine (25 g/day creatine with 25 g/day glucose) or placebo (50 g/day glucose) for 7 days followed by 14 days of maintenance (5 g/day creatine with 25 g/day glucose or 30 g/day glucose placebo).
[h=4]MAIN OUTCOME MEASURES:[/b]Serum T and DHT were measured and ratio calculated at baseline and after 7 days and 21 days of creatine supplementation (or placebo). Body composition measurements were taken at each time point.
[h=4]RESULTS:[/b]After 7 days of creatine loading, or a further 14 days of creatine maintenance dose, serum T levels did not change. However, levels of DHT increased by 56% after 7 days of creatine loading and remained 40% above baseline after 14 days maintenance (P < 0.001). The ratio of DHT:T also increased by 36% after 7 days creatine supplementation and remained elevated by 22% after the maintenance dose (P < 0.01).
[h=4]CONCLUSIONS:[/b]Creatine supplementation may, in part, act through an increased rate of conversion of T to DHT. Further investigation is warranted as a result of the high frequency of individuals using creatine supplementation and the long-term safety of alterations in circulating androgen composition. STATEMENT OF CLINICAL RELEVANCE: Although creatine is a widely used ergogenic aid, the mechanisms of action are incompletely understood, particularly in relation to dihydrotestosterone, and therefore the long-term clinical safety cannot be guaranteed.
[FONT="]
Three weeks of creatine monohydrate supplementation affects dihydrotestosterone to testosterone ratio in college-aged rugby players.
[/FONT]
[h=3]Abstract[/b][h=4]OBJECTIVE:[/b]This study investigated resting concentrations of selected androgens after 3 weeks of creatine supplementation in male rugby players. It was hypothesized that the ratio of dihydrotestosterone (DHT, a biologically more active androgen) to testosterone (T) would change with creatine supplementation.
[h=4]DESIGN:[/b]Double-blind placebo-controlled crossover study with a 6-week washout period.
[h=4]SETTING:[/b]Rugby Institute in South Africa.
[h=4]PARTICIPANTS:[/b]College-aged rugby players (n = 20) volunteered for the study, which took place during the competitive season.
[h=4]INTERVENTIONS:[/b]Subjects loaded with creatine (25 g/day creatine with 25 g/day glucose) or placebo (50 g/day glucose) for 7 days followed by 14 days of maintenance (5 g/day creatine with 25 g/day glucose or 30 g/day glucose placebo).
[h=4]MAIN OUTCOME MEASURES:[/b]Serum T and DHT were measured and ratio calculated at baseline and after 7 days and 21 days of creatine supplementation (or placebo). Body composition measurements were taken at each time point.
[h=4]RESULTS:[/b]After 7 days of creatine loading, or a further 14 days of creatine maintenance dose, serum T levels did not change. However, levels of DHT increased by 56% after 7 days of creatine loading and remained 40% above baseline after 14 days maintenance (P < 0.001). The ratio of DHT:T also increased by 36% after 7 days creatine supplementation and remained elevated by 22% after the maintenance dose (P < 0.01).
[h=4]CONCLUSIONS:[/b]Creatine supplementation may, in part, act through an increased rate of conversion of T to DHT. Further investigation is warranted as a result of the high frequency of individuals using creatine supplementation and the long-term safety of alterations in circulating androgen composition. STATEMENT OF CLINICAL RELEVANCE: Although creatine is a widely used ergogenic aid, the mechanisms of action are incompletely understood, particularly in relation to dihydrotestosterone, and therefore the long-term clinical safety cannot be guaranteed.
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