Creatine Monohydrate Increased DHT over 3 weeks

[andrewBwinter]

I found this study interesting using creatine monohydrate for a loading week and 2 maintenance weeks. If DHT is considered to be the more important T than FT, maybe that's why there is so much positive data on creatine. It remains to be seen if TRT and creatine might create the famed "one two punch" but I'll experiment and see. 25 g per day, ugh.

Results: After 7 days of creatine loading, or a further 14 days of creatine maintenance dose, serum T levels did not change. However, levels of DHT increased by 56% after 7 days of creatine loading and remained 40% above baseline after 14 days maintenance (P < 0.001). The ratio of DHT:T also increased by 36% after 7 days creatine supplementation and remained elevated by 22% after the maintenance dose (P < 0.01).

And the details:

Three weeks of creatine monohydrate supplementation affects dihydrotestosterone to testosterone ratio in college-aged rugby players - PubMed

Creatine supplementation may, in part, act through an increased rate of conversion of T to DHT. Further investigation is warranted as a result of the high frequency of individuals using creatine supplementation and the long-term safety of alterations in circulating androgen composition...

pubmed.ncbi.nlm.nih.gov

 

[madman]

I found this study interesting using creatine monohydrate for a loading week and 2 maintenance weeks. If DHT is considered to be the more important T than FT, maybe that's why there is so much positive data on creatine. It remains to be seen if TRT and creatine might create the famed "one two punch" but I'll experiment and see. 25 g per day, ugh.

Results: After 7 days of creatine loading, or a further 14 days of creatine maintenance dose, serum T levels did not change. However, levels of DHT increased by 56% after 7 days of creatine loading and remained 40% above baseline after 14 days maintenance (P < 0.001). The ratio of DHT:T also increased by 36% after 7 days creatine supplementation and remained elevated by 22% after the maintenance dose (P < 0.01).

And the details:

Three weeks of creatine monohydrate supplementation affects dihydrotestosterone to testosterone ratio in college-aged rugby players - PubMed

Creatine supplementation may, in part, act through an increased rate of conversion of T to DHT. Further investigation is warranted as a result of the high frequency of individuals using creatine supplementation and the long-term safety of alterations in circulating androgen composition...

pubmed.ncbi.nlm.nih.gov

Would not waste your time!

Natural 21M Very Low E2 Relative to T With Symptoms - Excel Male TRT Forum

Hello all, I'm at my wits end regarding low E2 symptoms which have been going on for at least 3 years, but have worsened: frequent urination (feels like I can't empty my bladder; underwear is always soaked), constipation, dry mouth, achy joints, complete loss of libido, ED. The blood...

www.excelmale.com

 

[andrewBwinter]

Hahaha, "search is your friend". I guess I didn't string together the proper words in proper order. Covered.

 

[bixt]

but I'll experiment and see. 25 g per day, ugh

No way man. 1/4 teaspoon is all you need (2 grams).

Such as calculated with the below calculator and many others googleable.

Creatine Supplement Dose Calculator – Pike Fitness®

pikefitness.com

The doses recommended on the container are just so you finish it faster and then buy more. The above (tiny) calculated doses are enough to cause full saturation and any extra is just pissed out (as creatinine).

 

[Deleted member 43589]

Creatine and DHT - Excel Male TRT Forum

Has it ever really been verified that creatine raises dht? Would've never thought so but seems like my prostate pings me after use now.

www.excelmale.com

https://www.excelmale.com/forum/threads/creatine-and-dht.26045/post-233585+

 

[andrewBwinter]

So, aside from the question of raising DHT with creatine, I will advise anyone to take 2-5g before bed and NOT in the morning. The results are, shall we say, "explosive"

 

[DaytonaJonah]

So, aside from the question of raising DHT with creatine, I will advise anyone to take 2-5g before bed and NOT in the morning. The results are, shall we say, "explosive"

Can you define a little more what you mean here? Thnx.

 

[andrewBwinter]

Explosive creatine diarrhea. For some reason, as the morning progresses, the cramping begins and the untimely release occurs.

However, having about 3gs before bed with some orange juice, no issue through the night.

 

[Systemlord]

I already got an increase in DHT from just being on Jatenzo compared to injections, the creatine I started two months ago is just icing on the cake.

 

[madman]

Thread 'Does creatine cause hair loss?'

Apr 24, 2025

* Overall, based on our current study and the majority of the evidence, creatine does not influence testosterone (free or total) and DHT

ABSTRACT

Background

Creatine is a widely used ergogenic aid that enhances muscle strength and lean mass. However, concerns have been raised about the potential role in promoting hair loss by increasing dihydrotestosterone (DHT). Currently, there is no direct evidence examining the relationship between creatine supplementation and hair follicle health. Therefore, the purpose was to determine the effects of 12...

• madman
• creatine; beta-alanine; nitrates; caffein; protein
• Replies: 8
• Forum: Nutrition and Supplements