compounded vs pharmaceutical

carkrazy

Member
Do you think there is any difference between compounded testosterone and pharmaceutical grade testosterone you would get from your local pharmacy other than the oils used? I've always been curious as to the quality and accuracy of the medication from a compound pharmacy.
 
Do you think there is any difference between compounded testosterone and pharmaceutical grade testosterone you would get from your local pharmacy other than the oils used? I've always been curious as to the quality and accuracy of the medication from a compound pharmacy.

As long as the compounded pharmacy is reputable and known to follow strict standards than there should be no difference between big pharma vs compounded.

Although there are various compounded pharmacies throughout Canada and the US that have been shown to be subpar.

Here is a study regarding compounded creams vs big pharma gels:


Accuracy of Testosterone Concentrations in Compounded Testosterone Products

Ethan D. Grober, MD, MEd, FRCSC,* Alaina Garbens, MD,* Andrea Božovic´, MSc, PhD,†‡ Vathany Kulasingam, PhD,†‡ Majid Fanipour, MD,* and Eleftherios P. Diamandis, MD, PhD,†‡§ *


In conclusion, the concentration of testosterone in testosterone creams and gels supplied by compounding pharmacies can be variable and potentially compromise the efficacy and safety of testosterone replacement therapy. Patients, physicians, and pharmacists need to be aware of such uncertainty. Testosterone concentrations in products supplied by Health Canada approved industry manufacturers were accurate and consistent over time. Our results highlight the need for further review of the current best-practice standards as they relate to training, credentialing, and licensure and ongoing quality control and feedback for compounding pharmacist
 

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I think a compounder is actually much more stringently regulated.

Big Pharma wants the compounders out of business. I talk to my pharmicist, and she says that compounders are getting harder to find beause of all the BS they push out about them. Its all about money, compounders were here long before the newest miracle drug.
 

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Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

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Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

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The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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