cold toes from TRT

Anyone have painfully cold toes while on TRT? I had it before, but it faded after I tapered and attempted a restart, but I seen to notice it again now that I am back on. Any thoughts on what could be causing it?
 
OP, I thought I saw some recent labs of yours around here? I'll do some looking, but if you have them please post them (or the link) up. Thanks :)
 
I've only been back on TRT for about 2 weeks after a 2 month PCT attempt. The labs I had before wereduring that time and estradiol was good but it was not the sensitive test.

If it is estradiol, the only thing I can think is that I have heard there can be an estrogen rebound after stopping Clomid and nolvadex. I have been taking about .5 mg arimidex weekly because I always responded well to a low dose before. However, I have noticed my face and nipples are puffier etc. I know labs are the only way to know for sure.

Have you ever heard of estradiol being higher when running the sensitive test or is it always lower then the standard? The reason I ask is my estradiol has never been above 40 and usually around 20 on the standard.
 
Cold toes can mean circulatory problems, low thyroid or side effect of beta blockers. I have never seen anything about estradiol and cold toes.
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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