CJC 1295/Ipamorelin and supplements

[DKNera]

Hey guys,

I'm currently taking CJC 1295+Ipamorelin and wanted to get some thoughts around taking other supplements with regard to using these peptides and avoiding food/insulin.

I inject right before going to bed at least 2 hours after eating to avoid insulin interfering. I normally take some supplements before I go to bed to help with sleep/mood, which include melatonin, GABA, 5-HTP, theanine (taken only with water).

Since I started the peptides, I stopped taking these supplements. Would there be any interference by taking the supplements and peptides at bedtime like before? Or should they be avoided on the days I use the peptides?

Thank you!

 

[JimGainz]

I took melatonin with the CJC/IPAm with no issues at all. I am not familiar with the other supplements but I believe the peptides work different channels.

 

[Hisham]

Why are you using the ipamorelin for ifi May ask? I just started it a week ago

 

[JimGainz]

Overall healing and body recomp. It did not bump my igf1 as much as ibutamoren but it does something. I feel great and my skin never looked better (not that I really cared but I’ll take it). I think it has a lot of benefits. I also take melatonin, TRT, etc. I just did a thread on using Ipamorelin and CJC with some Anavar and had fantastic results with that

 

[DorianGray]

I took melatonin with the CJC/IPAm with no issues at all. I am not familiar with the other supplements but I believe the peptides work different channels.

I've taken it also and I agree with this. I took all the other supplements I had taken before starting CJC/IP and noticed no difference in effects. On the other hand, I didn't notice any benefits such as Jim mentioned either.

 

[DKNera]

I took melatonin with the CJC/IPAm with no issues at all. I am not familiar with the other supplements but I believe the peptides work different channels.

Ah ok. Thank you for sharing.

 

[PeptideResearch]

Hi there,

That's a very common and smart question regarding timing and potential interactions. It's great that you're being so diligent about your research.

Many people find that getting the protocol right is key for CJC-1295 and Ipamorelin. For detailed, science-backed information on administration and peptide research in general, the team at Peptide Research Netherlands has a wealth of resources. It's a solid source to deepen your understanding of the mechanistic aspects.

Regarding your specific question about melatonin, GABA, 5-HTP, and theanine: From a mechanistic perspective, there is no known direct interference or negative interaction between these supplements and the activity of CJC-1295/Ipamorelin. Your supplements primarily work on different pathways (neurotransmitters, sleep-wake cycle) compared to the peptides.

The most crucial factor, as you've correctly identified, is avoiding insulin spikes to ensure optimal growth hormone release. Since you're taking your supplements only with water and well after your last meal, you are already mitigating that primary concern.

Many users in various forums anecdotally report continuing their sleep-support supplements without issue. The best approach is always to monitor your own body's response. You could consider reintroducing one supplement at a time to see how you feel.

Hope this helps you make an informed decision!