Can trt crash shbg?

[Arcane]

My current protocol is 30mg Test Cyp eod.

Before trt, my shbg was in the 80s n/mol. With every blood test over the past year it has gotten progressively lower 45 n/mol, 35, and now my most recent is 29. Im getting concerned that it might get TOO low (sub 20). Anyone have experience with this? Has trt lowered your shbg too much ?

 

[Cataceous]

Androgens do tend to reduce SHBG. This is an advantage for guys with high SHBG when they start TRT. For me SHBG dropped from the 40s nMol/L to about 30. If yours stays around 30 then that'a a good outcome. If it continues to drop then a further testosterone dose reduction would be a reasonable reaction. It's unlikely you need to have total testosterone over 900 ng/dL to feel good. If you can't find a happy medium then you might want to experiment with daily use of a cypionate/propionate blend. This is meant to imitate the variations seen in testosterone by healthy young men. The protocol allows for a reduction in the TRT dose while preserving peak levels.

 

[Arcane]

Androgens do tend to reduce SHBG. This is an advantage for guys with high SHBG when they start TRT. For me SHBG dropped from the 40s nMol/L to about 30. If yours stays around 30 then that'a a good outcome. If it continues to drop then a further testosterone dose reduction would be a reasonable reaction. It's unlikely you need to have total testosterone over 900 ng/dL to feel good. If you can't find a happy medium then you might want to experiment with daily use of a cypionate/propionate blend. This is meant to imitate the variations seen in testosterone by healthy young men. The protocol allows for a reduction in the TRT dose while preserving peak levels.

My Total Test is around 870 ng/dL

 

[Cataceous]

My Total Test is around 870 ng/dL

I was going by the 907 ng/dL you reported on 3/16. Not that 870 changes anything. It's still higher than most guys need.

 

[ivankonst2017]

Androgens do tend to reduce SHBG. This is an advantage for guys with high SHBG when they start TRT. For me SHBG dropped from the 40s nMol/L to about 30. If yours stays around 30 then that'a a good outcome. If it continues to drop then a further testosterone dose reduction would be a reasonable reaction. It's unlikely you need to have total testosterone over 900 ng/dL to feel good. If you can't find a happy medium then you might want to experiment with daily use of a cypionate/propionate blend. This is meant to imitate the variations seen in testosterone by healthy young men. The protocol allows for a reduction in the TRT dose while preserving peak levels.

I woudnt say lowering SHBG is a good thing, just on the contrary. The high SHBG can always be overcome with higher dose. For guys with lower SHBG often comes issues with injection frequency, high e2 symptoms and etc
Mine was 29 when I was doing EOD sustanon, now on bi-weekly enanthate Im affraid what it will be...

 

[Cataceous]

I woudnt say lowering SHBG is a good thing, just on the contrary. ...

If you have SHBG of 80 nMol/L and TRT lowers it to 30, which is typical for healthy young men, then it very likely is a good thing if other parameters are also ok.

 

[madman]

My current protocol is 30mg Test Cyp eod.

Before trt, my shbg was in the 80s n/mol. With every blood test over the past year it has gotten progressively lower 45 n/mol, 35, and now my most recent is 29. Im getting concerned that it might get TOO low (sub 20). Anyone have experience with this? Has trt lowered your shbg too much ?

Injecting higher doses of androgens would have a larger impact on driving down SHBG but even then it depends on the individual as some may notice a larger drop and others not so drastic.

Far from common that one would notice an absurd drop in SHBG using therapeutic doses of T.

Depending on dose T used/injection frequency it is not a given that SHBG will be driven down as some will only notice a slight drop or it stays around pre-trt levels.

Pre-trt my SHBG was 34 nmol/L.

I have been on trt for almost 5 years and even with running higher-end or slightly above TT/FT levels my SHBG sits at 30 nmol/L.

To be honest the c-17 alpha-alkylated orals such as methyltestosterone, oxandrolone, stanozolol, methandrostenolone, fluoxymesterone, and oxymetholone would have the biggest impact on driving down SHBG.


Many other factors other than T when it comes to altered SHBG.

 

[Match]

Para ser honesto, os orais alfa-alquilados c-17, como metiltestosterona, oxandrolona, estanozolol, metandrostenolona, fluoximesterona e oximetolona teriam o maior impacto na redução do SHBG.


Pode esclarecer melhor o que são os citados acima? Aqui SHBG alto, 62. Queria reduzir ao menos um pouco sem TRT