Can Testosterone quality affect acne?

Mike9876

Member
I'll try to keep this short. On TRT for almost 4 years. When I started, TRT in my country was non-existent. (these days there are a few clinics but none near me). So I've been doing it myself this whole time. I've been using pharma grade Test (cyp, enth) this whole time. About 2 months ago I had to get some UGL stuff because there was no pharma stuff available. Since then I've noticed some acne on my back and (weirdly) my head. Could the quality of the Test be causing this. I didn't even have much acne as a teenager and certainly none in the last 20 years so I'm trying to figure out what's causing it. The only thing I can think of is the change in Test. Note that my recent labs showed my Free and Total Test roughly what they've been the whole time (slightly down) and E2 (sensitive) was the same.

Note: I realise almost everyone on here is in US/Canada where TRT is very common and hence most will be using a prescription. So I understand not many will be able to offer advice. Just thought I'd give it a shot.
 
By any chance were you using cypionate before the acne, and the UGL stuff enanthate?

I ask because I saw a post on another forum a while back about enanthate converting more to DHT, compared to cyp. I cannot find more anecdotes.
 

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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