Can receptors being overwhelmed doing TRT be the reason Libido disappeared?

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kram22

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Like many here My libido started off great at the beginning of TRT but has since disappeared almost completely like it was b4 i started TRT. I'm using btw 50-60mg of test cyp along with 500iu of HCG twice per week. I read that its possible my receptors are overloaded with T and could be the reason why? My blood numbers are all pretty good so I can't understand what the hell the problem is. Any info on this theory regarding the receptors and how to improve their sensitivity?
 
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That's what my doc told me, and that is why he had me switch from test cyp to transdermal cream so that I would get a greater swing in my T levels. More like that of a young healthy man as Dr. Crisler has said in his book (he is not my doc).

That said, a daily schedule still doesn't work for me and I have to take a week or 2 off of T in order to get reset and respond the the T when I start up again. This has been a really frustrating experience.
 
Define the timeframe you refer to as starting as being "great".

I bet you'll say 0 - 3, maybe 4 weeks as "great".

It wasn't even that long...It always just lasted a few days and then fell off again. The only time it returned was when I stopped the TRT briefly and then restarted but when i do the TRT/HCG consistently I barely get any boost in libido at all.
 
It wasn't even that long...It always just lasted a few days and then fell off again. The only time it returned was when I stopped the TRT briefly and then restarted but when i do the TRT/HCG consistently I barely get any boost in libido at all.

Exactly my experience.
 
I'm in the same boat..Haven't tried the Transdermal though but I'm was considering trying Test Prop instead or just stopping TRT all together but I'm really just grasping at straws at this point. All the experts say don't cycle on TRT but I'm not sure what else to do here. Its VERY freaking frustrating!
 
Exactly my experience.

You have far too many posts here to be practicing this start/stop method, pardon me but you should know better, atleast I expect that you would know that this is not productive.

In the first week to two weeks, the exo T is combining with your Endo T and is why you feel great and why you stop feeling great is because at that ~2 week point is when your body production stops and you're on exo T entirely.
 
You have far too many posts here to be practicing this start/stop method, pardon me but you should know better, atleast I expect that you would know that this is not productive.

I'm not ready to give up on my sex life entirely yet, and this seems to be to only way to have any libido at all.

In the first week to two weeks, the exo T is combining with your Endo T and is why you feel great and why you stop feeling great is because at that ~2 week point is when your body production stops and you're on exo T entirely.

This may be true for some, but I have the labs to prove this isn't the case with me.
 
Then maybe increasing the HCG would be the answer since that's what keeps your Endo T production going? Believe me I don't want to stop TRT. Getting that initial boost and then losing it sucks...Now i'm spending all my focus trying to get back to that feeling..believe me I'm committed to improving myself anyway I can.
 
Then maybe increasing the HCG would be the answer since that's what keeps your Endo T production going?

My doc felt that HCG mono was the best way to go to try and help me, IF my body could still produce adequate amounts of T. I tried it, and I did have a small initial boost in libido but I could only get my total T up to about 350 so he had me change to T cream and low dose HCG.

Now i'm spending all my focus trying to get back to that feeling

I know that feeling, it's been driving me nuts for 3 years now.
 
Like many here My libido started off great at the beginning of TRT but has since disappeared almost completely like it was b4 i started TRT. I'm using btw 50-60mg of test cyp along with 500iu of HCG twice per week. I read that its possible my receptors are overloaded with T and could be the reason why? My blood numbers are all pretty good so I can't understand what the hell the problem is. Any info on this theory regarding the receptors and how to improve their sensitivity?

What did your labs show? Total and free testosterone, shbg, estradiol/sensitive assay?
 
Libido is heavily tied to DHT levels and I have read about some guys now using a combination of shots and topicals to be able to both have high enough total T levels (due to the shots) and having enough DHT to have a decent libido (due to the topicals)

I know it sounds like a lot of work and I have not tried it myself, but it seems to make logical sense as it theoretically gives you the best of both methods.
 
Libido is heavily tied to DHT levels and I have read about some guys now using a combination of shots and topicals to be able to both have high enough total T levels (due to the shots) and having enough DHT to have a decent libido (due to the topicals)

I know it sounds like a lot of work and I have not tried it myself, but it seems to make logical sense as it theoretically gives you the best of both methods.

Proviron is a DHT yeah? I've found that it give me rock hard erections, and HCG always seems to get libido going again, just haven't used HCG long term yet.
 
The reason why libido increases when a man starts a TRT protocol is the Dopamine rush he gets in the brain but in time that subsides.

What are your E2, DHT and Prolactin labs???

All three of these can impact libido and about 1000 other things.
 
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I'm not ready to give up on my sex life entirely yet, and this seems to be to only way to have any libido at all.



This may be true for some, but I have the labs to prove this isn't the case with me.

That's bizarre. Do you have labs posted in another thread, labs within days and weeks of each other, on T, off T, and so forth? I'd like to read that.
 
karma22,

Try cream 20% (200 mg) on your scrotum. I got my DHT really high, which I believe will help drive sex drive. At least it did for me, however, my total T never got above 500 with cream. I notice my sex drive is less with Test Cyp, but workouts stronger, tightness to muscles...My guess is DHT is lower with Test Cyp and that might be some of the reason for loss of sex drive.
 
DHT is actually my next area to see what I can do with it, trying Creatine, but subjectively, nothing. When I was tested in Aug my DHT came back @ 36 (16-79 range). Now that I'm correcting my lack of Cortisol, this is my next area as I've eliminated any Thyroid matters. I may ask Defy if they'd give me a little topical to try with my injections.
 
I am thinking about asking Defy for some topical to go with my injections as well during my next consult. Just on shots alone over the last 5 years my DHT is normally in the middle of the 16-79 range, but I read about a lot of guys that have a huge libido by getting their DHT at or above the top of the range.

I can definitely say that TRT with shots and HCG and good E2 levels has never done much of anything for my libido (basically it's not any better than what I had with Low T), so I look forward to anything that may help.
 
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That's what my doc told me, and that is why he had me switch from test cyp to transdermal cream so that I would get a greater swing in my T levels. More like that of a young healthy man as Dr. Crisler has said in his book (he is not my doc).

That said, a daily schedule still doesn't work for me and I have to take a week or 2 off of T in order to get reset and respond the the T when I start up again. This has been a really frustrating experience.

When you talk about a swing in T levels do you mean like a surge or like highs and lows?

It's interesting to me because i've heard that propionate esters mimic the bodys natural production more, and everyone seems to be all about keeping blood levels stable with more frequent injections but maybe thats the problem ?
 
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