read that at high doses of hCG for a long period of time,
Your leyiding receptor die.
so I want to make sure that I'm safe injecting hCG.
perhaps only in Poland are so afraid of hcg.
leyidin receptor exogenous testosterone is produced, because the inquires.
small penis is 12cm
Here's why this is dose is not a good idea:
1. Down regulation and desensitization of leydig receptor cells resulting in lower endogenous testosterone production
2. Increased levels of intratesticular estrogen which an AI is largely ineffective in managing
3. Increased levels of estrogen levels...period
Men have a given amount of leydig cell receptors so there is only so much of the peptide that will be effective. This is not a "if some is good more is better" solution...in fact, like testosterone, it's the opposite.
Most well trained Docs in TRT know that any dose over 500 units is a waste and some even go so far as to say 350 units is the optimal amount for the testes to function properly.
Just my $0.02.
Nelson, what do you think?
Is there a difference between intramuscular and subcutaneous injections with Pregnyl ???
No difference
Predict estradiol, DHT, and free testosterone levels based on total testosterone
This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.
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A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.
Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.
The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.
Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.
DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038