Can Anastrozole cause nausea and breathlessness?

[raw74]

Hi guys,

I have been on doctor prescribed and monitored TRT for the last 4 months. My current protocol includes TE (250mg per week) and Anastrozole (0.5mg twice per week).
Lately I feel short of breath and have nausea at times throughout the day- especially during and after training.
My recent blood work appears normal except for a low Alk Phos 41 U/L (50-110), an elevation in WBC 9.3 (4.0-11.0) and Ferritin 471 ug/L (20- 300).
I have had a chest x-ray, ECG, stress ECG and upper abdomen ultra sound which all appear normal except for slight LVH (diagnosed by cardiologist but still in normal reference range- says common for someone who has lifted heavy for a long time- doesn't think its to blame for symptoms).
Are these symptoms commonly seen with use of Anastrozole?

 

[Nelson Vergel]

I bet you have high hematocrit (your high ferritin makes me think so). Do you know what it is?

Nausea is not a common side effect of testosterone or anastrozole. What is your blood pressure? Beathlessness can be caused by high blood pressure. Measure it right when you work out, not at rest.

LVH is common in athetles and bodybuilders. I also have it. It does not explain your symptoms.

You may also be overdosing on anastrozole. Get your estradiol tested by ultrasensitive test.

 

[raw74]

Hi Nelson,

Thanks for the prompt reply.

I suspected hematocrit but my Hct is 0.48 (0.40- 0.54).

The cardiologist suspected high BP- it is sometimes elevated (140-150/85-90) and I imagine much higher when I train?
I have actually just completed a 24 hour BP monitor so will find out the results this week.

Can the TE and Anastrozole be elevating BP?

 

[Gene Devine]

Testosterone supplementation and an AI will not cause elevated BP.

Something else is at play here. Are you taking any other meds or performance supplements?

250 mg of test per week is high for a TRT protocol; why is that?

1 mg of an AI weekly on 250 mg of Testosterone may not tank E2 but it can still happen.

Do you split your 250 mg injections into 125 mg twice weekly?

If so, take the .5 mg of the AI 24 hours after each injection.

 

[Nelson Vergel]

raw74

Hematocrit is usually over 42. You say yours is 0.48?

 

[raw74]

Hi Gene,

Thanks for the reply.

No other pharmaceutical supplementation at the moment and no performance supplementation around training.

Initially we tried a few different time frames between injections- reassessed symptoms and checked blood chemistry accordingly- the 250mg TE every 7 days was the appropriate protocol for me.

The TE that I am prescribed is Primoteston Depot (250mg redi-ject) so it is administered once per week only.

Nelson the reference range for Hct on my blood chemistry is (0.40- 0.54) so is it 40% to 54%?