World renowned Abdulmaged M. Traish!
Great interview!
As usual free testosterone is where it's at!
Nelson we need to inform Dr.Traish or better yet all of the uros, endos and GPs about discounted labs LMFAO!
Listen closely 7:20-15:17
* it's easy to measure Total Testosterone, it's not easy to measure Free Testosterone
* it's so easy to measure Total Testosterone, it's really COMPLEX to measure Free Testosterone
*it's the Free Testosterone that matters not the Total
Feeling low on energy, struggling to lose weight, or facing sexual health concerns? It might be low testosterone!
Join Dr. Anne Truong as she chats with Dr. Traish, Emeritus Professor of Urology at Chobanian and Avedisian School of Medicine, about all things testosterone. Dr. Traish provides clear, science-backed advice to help you optimize your testosterone levels and improve your overall health.
Chapters:
00:00 - Testosterone and its importance for men's health, aging, and overall well-being
07:32 - Testosterone measurement and its limitations
14:10 - Individual testosterone levels and how they respond differently to different levels of testosterone
19:12 - Testosterone levels and their interpretation, with criticism of the 300 ng/dL cutoff point
25:16 - Testosterone and prostate cancer, with evidence showing no link
32:54 - Testosterone therapy safety and effectiveness
38:38 - Testosterone therapy for women, despite FDA restrictions
44:55 - Testosterone replacement therapy for women, including stigma and lack of products
51:18 - Lifestyle and exercise impact on testosterone levels and sexual health
57:46 - Testosterone levels, symptoms, and natural remedies for men
01:02:00 - Outro
www.excelmale.com
IMPACT STATEMENT
Measurement of free hormone (FH) concentrations in biological samples presents a challenge to the clinical laboratory. FH concentrations are generally very low, requiring use of sensitive and specific techniques. Furthermore, special attention must be placed on the equilibrium between free and protein-bound hormone when separating and analyzing in vitro. This review will enhance the readers’ understanding of the current state of mass spectrometry-based methods for the measurement of FHs. The advantages and disadvantages of different separation techniques and sample preparation methods are discussed, as well as clinical conditions in which measurement of FH is warranted.
www.excelmale.com
www.excelmale.com
www.excelmale.com
www.excelmale.com
www.excelmale.com
www.excelmale.com
www.excelmale.com
www.excelmale.com
Great interview!
As usual free testosterone is where it's at!
Nelson we need to inform Dr.Traish or better yet all of the uros, endos and GPs about discounted labs LMFAO!

Testosterone, Free (Equilibrium Dialysis) and Total, MS - Most Affordable and Accurate Test
Get an affordable and accurate testosterone test results with our Total Testosterone, M and Free (Equilibrium Dialysis) test. Visit DiscountedLabs.com for more information.
Listen closely 7:20-15:17
* it's easy to measure Total Testosterone, it's not easy to measure Free Testosterone
* it's so easy to measure Total Testosterone, it's really COMPLEX to measure Free Testosterone
*it's the Free Testosterone that matters not the Total
Feeling low on energy, struggling to lose weight, or facing sexual health concerns? It might be low testosterone!
Join Dr. Anne Truong as she chats with Dr. Traish, Emeritus Professor of Urology at Chobanian and Avedisian School of Medicine, about all things testosterone. Dr. Traish provides clear, science-backed advice to help you optimize your testosterone levels and improve your overall health.
Chapters:
00:00 - Testosterone and its importance for men's health, aging, and overall well-being
07:32 - Testosterone measurement and its limitations
14:10 - Individual testosterone levels and how they respond differently to different levels of testosterone
19:12 - Testosterone levels and their interpretation, with criticism of the 300 ng/dL cutoff point
25:16 - Testosterone and prostate cancer, with evidence showing no link
32:54 - Testosterone therapy safety and effectiveness
38:38 - Testosterone therapy for women, despite FDA restrictions
44:55 - Testosterone replacement therapy for women, including stigma and lack of products
51:18 - Lifestyle and exercise impact on testosterone levels and sexual health
57:46 - Testosterone levels, symptoms, and natural remedies for men
01:02:00 - Outro
Direct Measurements of Free Hormones Using Mass Spectrometry-Based Methods
Only at Excel, are we gonna take you deep! Clinical Utility and Analytical Aspects of Direct Measurements of Free Hormones Using Mass Spectrometry-Based Methods (2022) Mark M. Kushnir, Heather A. Nelson, and Kelly Doyle Background The free hormone (FH) hypothesis states that hormone...

IMPACT STATEMENT
Measurement of free hormone (FH) concentrations in biological samples presents a challenge to the clinical laboratory. FH concentrations are generally very low, requiring use of sensitive and specific techniques. Furthermore, special attention must be placed on the equilibrium between free and protein-bound hormone when separating and analyzing in vitro. This review will enhance the readers’ understanding of the current state of mass spectrometry-based methods for the measurement of FHs. The advantages and disadvantages of different separation techniques and sample preparation methods are discussed, as well as clinical conditions in which measurement of FH is warranted.
Comparability of Free Testosterone Measurements- Results of the Interlaboratory Study
https://academic.oup.com/clinchem/article/70/Supplement_1/hvae106.074/7760719 Assessment of free testosterone (FT) has been recommended as a biomarker for diagnosis and management of hypogonadism and female hyperandrogenism. Reliable laboratory measurements are essential for correctly...

CDC STANDARDIZED TOTAL T and ESTRADIOL ASSAYS and soon to be FREE TESTOSTERONE!
How the CDC Clinical Standardization Programs Are Improving Hormone Tests - AACC.org WHAT PROGRESS HAS CDC MADE WITH STANDARDIZING TOTAL TESTOSTERONE AND ESTRADIOL TESTS? Since HoSt began in 2010, CDC has had more than 350 participants in 15 countries. Participants have shown measurable...

Free Testosterone - Harmonize diagnostic efforts in steroid hormonology
Measurement and reporting of clinical testosterone diagnostics: a European survey (2023) *Three fractions circulate in plasma: the unbound (free) fraction, the fraction bound to specific binding proteins, such as sex hormone-binding globulin (SHBG) and vitamin D binding protein (DBP); and the...

Role of SHBG in the free hormone hypothesis and the relevance of free testosterone in androgen physiology
Role of sex hormone‑binding globulin in the free hormone hypothesis and the relevance of free testosterone in androgen physiology (2022) N. Narinx · K. David1, · J. Walravens · P. Vermeersch · F. Claessens · T. Fiers · B. Lapauw · L. Antonio, · D. Vanderschueren Keep in mind this is...

Testosterone Blood Test Results - Time of Day?
I have taken two blood tests over the last two weeks with very different results. I appreciate levels fluctuate all the time from day, week, month and clearly hourly, so getting a consistent results is almost impossible. I was very surprised at the difference in levels! Test 1 - taken at...

Understanding the Variations of LH, FSH, and Testosterone: Implications for Diagnostic Accuracy
Understanding the Variations of Reproductive Hormones: Implications for Diagnostic Accuracy Reproductive hormones play a crucial role in the functioning of the human body, influencing various physiological processes and reproductive health. Recent studies have shed light on the complex nature of...

New Perspectives in the Diagnosis and Management of Hypogonadism
Only at Nelson's domain. Enjoyed this one. Dr. Khera and Dr. Mulhalll, are two giants in the field here!

Testosterone Therapy and Erythrocytosis - the most common dose-limiting effect of testosterone therapy
https://www.thebloodproject.com/cases-archive/testosterone-therapy-and-erythrocytosis-2/ Introduction Androgens play a crucial role in the development and maintenance of: Male reproductive and sexual functions Body composition Erythropoiesis Muscle and bone health Cognitive function...
