Beyond the Semen Analysis: New Tests of Sperm Function

madman

Super Moderator

Larry I. Lipshultz, MD, Professor of Urology and Chief of the Scott Department of Urology’s Division of Male Reproductive Medicine and Surgery at Baylor College of Medicine in Houston, Texas, critically examines the limitations of traditional semen analysis in evaluating male infertility and advocates for the adoption of advanced diagnostic techniques. In this 23-minute presentation, Dr. Lipshultz asserts that traditional semen analysis is outdated and should be supplemented with new advanced, functionally informative tests to enhance diagnostic accuracy and patient care in infertility treatment.





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* so the standard semen analysis has modest predictive value if any for live birth rates

* so we need new innovative tests and that's what I would like to focus on today what's new



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Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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