Best time of day for Estradiol test?

GetWell

New Member
My doctor has finally agreed to let me get the ultrasensitive estradiol test. I have been on TRT for 15 years +/-. Is there a certain time of day that would be most ideal for getting my blood drawn? I ask this because I know there are wide fluctuations in testosterone levels between morning and evening. Is the same true of estrogen?
--Glenn
 
E2 serum levels will be somewhat more stable as compared to Testosterone so that being said it really doesn't matter when you get it tested.

Remember, all blood work in a snap shot it time and you'd really need numerous labs to get a more average but truer picture of things.
 
Thanks for the helpful info, guys. Test done this afternoon. 25 pg/ml. This lab has a reference range for men of 8-43. Any thoughts?
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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