A doctor actually prescribed me 1mg of arimidex once per week before to lower my E2. I am not on TRT and my E2 was measured at 30 and 36 before. Range was from anything <or =40. Just wandering if my doctor was stupid for prescribing me that amount of arimidex a week when I'm not on TRT. I also felt like crap after I took the arimidex. Very bad anxiety and my chest felt extremely tight and i could't sleep to save my life. Does arimidex cause bad side effects when you take it? And is it known to make guys feel like crap when they take it? After I took it once I am never going to take arimidex again due to how crappy it made me feel. I have feeling I shouldn't of even needed it in the first place because my E2 wasn't super high.