Are there any legitimate proven reasons why cyp wouldn't work for someone, but another ester or delivery system would?

[Jov220]

Is there any proven reason, besides anecdotal experiences, where someone would need to use something like prop, gels, pellets, etc over just cypionate injections? If proper levels can be achieved with cyp, why would it make a difference?

Also, I watched a video where Dr Gordon was saying that pregnenolone and DHEA supplementation was 100 percent necessary if you're on T for any appreciable amount of time, is this true?

 

[Guided_by_Voices]

I think "proven" is an unjustifiably high bar, however it is widely accepted that creams, for example will produce a meaningfully higher level of DHT is some cases and that this can make the difference between working and not working for some people.

Also, many things we now take for granted were established as valuable by anecdote, especially given the generally poor design quality of many health-related studies. As Dr. Doug McGuff says, "science follows anecdote".

Regarding DHEA, try it and see. For me it seems to be a big benefit but it may not be for everybody. Unfortunately there are rarely 100% certain conclusions when it comes to health and hormones.

 

[Gman86]

I’m wondering this exact thing. A guy @Paco1973 on here was saying that he feels dramatically better on propionate vs cypionate.

 

[bbex2014]

high dosage transdermals will effect most people differently than the longer injectable esters commonly used of cyp and enanth. Like g_b_v said, transdermals raise dht much higer than injections. I've never used test prop before, but I have used test no ester, and that was quite neuro stimulating to me.

 

[Guided_by_Voices]

And having started on Test Prop myself, I think it is MUCH easier to find the "proper level" on test prop than on test cyp. When you're just starting you have to use trial and error to find the right level and a shorter ester makes it mush easier to adjust, so in that sense, even if one reacts the same to the ester, there is still a big difference between the two.

 

[TorontoTRT]

Enanthate over Cyp any day. To me Cyp feels like injecting water. On paper cyp gives better numbers but this doesn’t translate to real life experience.

 

[Gman86]

Enanthate over Cyp any day. To me Cyp feels like injecting water. On paper cyp gives better numbers but this doesn’t translate to real life experience.

So interesting. I believe you though. Just wondering how this could be the case. Were both cyp and enanthate prescribed? Were they the same brand? So your numbers come back lower on enanthate?