Anybody using antidepressants with TRT? Similar to tramadol?

trtthings

Active Member
I found that tramadol has a profound effect on my mood.

It works by increasing serotonin, norepinephrine as well as working on one type of opioid receptor.

Does anybody know of a similar AD?
 
Tramadol is not an antidepressant, it is an opioid. Not sure where you are getting it, but a doctor should be prescribing it and it is intended to be used no more than four days as it is addictive. You may want to look into something else with a psychiatrist. No one should be playing doctor with any psych meds. Very dangerous practice.
 
Tramadol is not an antidepressant, it is an opioid. Not sure where you are getting it, but a doctor should be prescribing it and it is intended to be used no more than four days as it is addictive. You may want to look into something else with a psychiatrist. No one should be playing doctor with any psych meds. Very dangerous practice.

Indeed but it works very similar. I'm not taking it every day though, it's just an effect I observed, so I looked it up and saw it affects serotonin and norepinephrine as well. So similar to an SNRI but with added opioid receptor activity.
 
There are many drugs that have effects on serotonin. When you take combinations of drugs that increase serotonin you may end up with serotonin syndrome.
 
I found that tramadol has a profound effect on my mood.

It works by increasing serotonin, norepinephrine as well as working on one type of opioid receptor.

Does anybody know of a similar AD?
Tramadol is a narcotic man. It’s prescribed for pain relief particularly after surgical procedures. It is highly addictive. Sure it may help you feel better but that is the desired effect. Any opioid will make you feel better until you find yourself standing in line for methadone or slipping suboxone strips under your tongue. Definitely not meant for emotions management or depression.
 

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Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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