Any Testosterone Propionate Compounding Pharmacies left?

[FunkOdyssey]

Not true whatsoever as of last October. Chinese government shut down the underground raw steroid industry. There's no new hormones being made, so suppliers are clearing out inventory. Amongst the ones selling straight oils. TONS of fake stuff on the market now. Janoshik is proving this all over the bodybuilding forums.

Precursors to making fentanyl are used in hormone synthesis. Which is what started all this. Those chemicals are gone forever. Lots of panic on those other forums

This affected AAS like primo and masteron, not testosterone (which is what we're discussing here), and the reputable vendors simply admitted that they're out of stock on those other compounds rather than sell anything fake. The state of UGL testosterone remains very healthy.

 

[madman]

I was using Prop Subq ED @ .13ml (I've been as high as .2ml and as low as .1ml, but .13ml was enough for me where I felt best).... I like prop precisely because of the trough (high in early day and low at night which is closest to natural test peak/low levels)... I've always struggled with sleep while on trt but for me prop is the lesser of the other 2 evils from Enan and Cyp, as I feel I get a little bit better sleep on prop.. also, I think my E is easier to control as I don't really need Adex like I do on enan/cyp and I don't carry alot of water weight. PS- I jab whenever I wake up... I work out in mornings during week so I inject at 6am and on weekend usually around 8 or 9am

PS- if you search on Excel and can find it, a couple years ago I've posted a bunch of lab numbers measuring peak and trough on Prop and Cyp.

I like prop precisely because of the trough (high in early day and low at night which is closest to natural test peak/low levels)


This is false!

This myth needs to be put to rest!

TP in no way closely mimics the TT 24 hr circadian rhythm of normal young adult males.

Although natty endogenous peak T is achieved upon awakening in the early am and remains moderately elevated until it starts to decline gradually during the late morning and afternoon reaching nadir (lowest point) in the evening levels will start to GRADUALLY RISE AGAIN OVERNIGHT!

Testosterone levels GRADUALLY RISE OVERNIGHT peaking in the early AM!

Even when it comes to the peak achieved with TP levels will shoot up quickly there is NO GRADUAL RISE!

Top it off that many injecting daily prop are hitting way too high a peak and more importantly still running around with a high/very high trough!

If you are hitting a high/very high trough on TP you are clearly overmedicated.

As I have stated numerous times on the forum over the years when it comes to most closely mimicking the 24 hr natty circadian rhythm of a healthy young male the transdermal T-patch (Androderm®) holds the title!


* The TT concentration produced by the Androderm® transdermal patch applied to the skin of the back, stomach, upper arms, or thighs nightly before retiring to sleep more closely reproduces the normative TT circadian pattern of young adult males than any of the other marketed PA-TRTs. Following application, TT concentration progressively rises during sleep and peaks around the time of morning awakening; it progressively declines during late morning and afternoon, reaching its nadir (Cmin) in the evening before the next scheduled patch application (Figure 3D).


* The TT level produced by the Androderm® transdermal patch system when applied as recommended in the evening before bedtime most closely simulates the normal physiologic pattern. In this regard, the high and low limits of normal TT in the graph of this PA-TRT found in the package insert are unique (Figure 3D); they are depicted in a time-varying cyclic, rather than a time invariable constant, manner that takes into consideration the normal high-amplitude TT circadian variation of diurnally active healthy young men(https://www.accessdata.fda.gov/ drugsatfda_docs/label/2011/020489s025lbl.pdf). This is in distinct contrast to the manner in which the high and low limits of normal are depicted in the package insert of all the other PA-TRTs (Figure 2A-2F and Figure 3A-3C), that is, as constant values consistent with the presumed homeostatic perspective of human biology and endocrinology. Such a homeostatic perspective drives the recommended procedures of dose assessment and titration, although with inconsistencies between the different PA-TRTs in the recommended time of day when to conduct them (Table 2).

Thread 'Does Patient-Applied TRT Pose Risk for Blood Pressure Elevation?'

Nov 12, 2022

Does Patient-Applied Testosterone Replacement Therapy Pose Risk for Blood Pressure Elevation? Circadian Medicine Perspectives (2022)
Michael H. Smolensky, Ramon C. Hermida, Linda Sackett-Lundeen, *Ramon G. Hermida-Ayala, and Yong-Jian Geng


ABSTRACT

We reviewed medication package inserts, US Food and Drug Administration (FDA) reports, and journal publications concerning the 10 nonbiosimilar patient-applied (PA) testosterone (T) replacement therapies (TRTs) for intraday serum T patterning and blood pressure (BP) effects. Blood T concentration is circadian...

• madman
• trt; blood pressure; hypertension
• Replies: 8
• Forum: Testosterone and Men's Health Articles

• 

You can throw TP in there too!

Figures 2A-2F depict the TT 24 h pattern achieved by the 6 different solution and gel PA-TRTs, and Figures 3A-3D depict the TT 24 h pattern achieved by the buccal tablet, oral capsule, transdermal patch, and subcutaneously injected PATRTs. There are substantial differences between the therapies in the derived TT 24 h pattern; moreover, all but one of them differs either somewhat or greatly from the normative one of diurnally active young adult males, which is defined by: (i) elevated and near peak TT level during nighttime sleep, (ii) peak TT level around the time of morning awakening, (iii) moderately elevated TT level during the initial hours of wakefulness, (iv) reduced TT level in the late afternoon, and (v) lowest TT level in the evening. Based upon these criteria, only the Androderm® transdermal patch (Figure 3D), when applied in the evening (∼22:00 h) as recommended, closely mimics the TT circadian rhythm of normal young adult males.

Post in thread 'T.Cyp 100 mg/week - Night sweats, anxiety'

Oct 8, 2023

This is good advice. More frequent injections never worked for me either. Always made me feel like complete crap. High resting heart rate, insomnia, moody, sexual side effects. And many more. With esters like cypionate , and enanthate you don’t need to inject more often. The problem with more often injections is that your levels are always peaked. That’s not healthy at all. The body needs fluctuations. Injecting every day or every other day does not mimic natural production at all. All that advice is just based on bro science B.S.

With esters...

• madman

• 

 

[t_spacemonkey]

I too abandoned my trt clinic because no more Tprop. and saving lots of money by going UGL. blood work via my general doc, for pennies through insurance.
i also felt like shit on TC. no clue why. i do believe while Tprop does not mimic the natural peaks/lows, it provides a large enough daily swing to give your body a little 'break'. 'you need to maintain a stable level' is complete nonsense pushed by all kind of T 'gurus'. yes, you dont want weekly swing, but daily are totally fine. the morning shot peaks 2-3h post and tapers off at night a bit

 

[twohunglow81]

This affected AAS like primo and masteron, not testosterone (which is what we're discussing here), and the reputable vendors simply admitted that they're out of stock on those other compounds rather than sell anything fake. The state of UGL testosterone remains very healthy.

Noooo it is not my friend. Im well aware of what were discussing here, which is why im posting this to help the uninformed stock up on UGL testosterone if they need it. Janoshik himself has posted many threads about the fakes on multiple forums. did you read those? All testosterone esters need the exact same precursors as masteron and primo to be synthesized. Those are now controlled substances by the chinese government without special licensing. Primo and masteron were the first to disappear from the UGL scene though. Theres no more raw powders of ANY kind being made for UGLs. Testosterone included. Once these UGL sources are out of oils, they are out of business if they dont sell peptides. The Chinese government cracked down hard.

 

[t_spacemonkey]

Noooo it is not my friend. Im well aware of what were discussing here, which is why im posting this to help the uninformed stock up on UGL testosterone if they need it. Janoshik himself has posted many threads about the fakes on multiple forums. did you read those? All testosterone esters need the exact same precursors as masteron and primo to be synthesized. Those are now controlled substances by the chinese government without special licensing. Primo and masteron were the first to disappear from the UGL scene though. Theres no more raw powders of ANY kind being made for UGLs. Testosterone included. Once these UGL sources are out of oils, they are out of business if they dont sell peptides. The Chinese government cracked down hard.

it seems that mast/primo are gone for the most, but reading info from various UGL's that it slowly is picking up. can't find confirmed into, but it seems that some of the raws are being used to make fentanyl as well, and there is the crackdown. T shipments do seem however to come through according to UGL sources. where there is demand there will be supply, but having a 12months backup of Test is not a bad idea. I don't see a way the market going dark completely, that never happened to any drugs in history

 

[FunkOdyssey]

Noooo it is not my friend. Im well aware of what were discussing here, which is why im posting this to help the uninformed stock up on UGL testosterone if they need it. Janoshik himself has posted many threads about the fakes on multiple forums. did you read those? All testosterone esters need the exact same precursors as masteron and primo to be synthesized. Those are now controlled substances by the chinese government without special licensing. Primo and masteron were the first to disappear from the UGL scene though. Theres no more raw powders of ANY kind being made for UGLs. Testosterone included. Once these UGL sources are out of oils, they are out of business if they dont sell peptides. The Chinese government cracked down hard.

I just don't buy it. I'm on multiple forums and have yet to see any indication from any reputable source that testosterone supplies are dwindling or threatened. The manufacture of testosterone esters will never cease, because these have legal and legitimate end customers, and some amount of these will always be diverted to the UGL market.