Any guys here with high SHBG?

Larger dosages will naturally decrease those with high SHBG, a larger dose of T brought my SHBG a bit too low for my liking. It's going to make an AI even more important if one is going to control E2 from larger dosage in an attempt to bring down SHBG.
 
In my notes I have:
Keep SHBG in check with Chrysin, Quercetin (inhibit aromatase), Nettle root, Fishoil, protein
Combining nettle root with Pygeum results in a stronger synergistic inhibition of SHBG binding.
Nettle prevents SHBG binding to cell membrane and therefore reduces hormone related cancers

Regarding low free-T and high SHBG you could try:
DHEA 15-20mg daily
VitD3 5-10k iU
stinging nettle Root (mixed results)
Eat High protein, Low glycemic carbs

I can't validate any of this as i have been focused on other things recently but it is something I will be looking at for myself soon.
 

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HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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