Anastrazole

I changed my twice a week dose to M-W-F and it has made me feel much better.

BigBamBoo,

On your MWF schedule, do you inject at evenly spaced times on injection days (M morning W afternoon F evening), or at similar times (M morning W morning F morning/evening)?

Same weekly dose as E3.5D?
 
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Yes, I inject Monday 7am, Weds 3pm, and Friday 9pm.

I know, that is not exactly evenly spaced, but close enough for me.

I am doing 50mg on those days. I feel MUCH better on this protocol.
 
Yes, all my high high E2 symptoms are gone. No more sore nipples, acne, hard time reaching orgasm, etc.

I need to pull labs...keep forgetting to order them. But just based on symptoms, I am pretty convinced it is lower.

Even if it is not, I would not mess with anything at this point because it is pretty much the best I have felt since starting TRT.
 
Yes, all my high high E2 symptoms are gone. No more sore nipples, acne, hard time reaching orgasm, etc.

I need to pull labs...keep forgetting to order them. But just based on symptoms, I am pretty convinced it is lower.

Even if it is not, I would not mess with anything at this point because it is pretty much the best I have felt since starting TRT.
What dosage do you do at each injection? And do you HCG at all?
 
I don’t think it really does much for. It has made me bloated in the past.

Since stopping it, my nuts actually hang lower and feel fuller and larger.

Pretty much nothing in my TRT has been “normal”. As a high SHBG guy, most say less frequent, larger doses of T is best. Not in my case.

I was told HCG would increase my ejaculation volume and force...nope.
I use to have a very large load and force prior to TRT. That has been one of my major gripes with TRT.
 
I don’t think it really does much for. It has made me bloated in the past.

Since stopping it, my nuts actually hang lower and feel fuller and larger.

Pretty much nothing in my TRT has been “normal”. As a high SHBG guy, most say less frequent, larger doses of T is best. Not in my case.

I was told HCG would increase my ejaculation volume and force...nope.
I use to have a very large load and force prior to TRT. That has been one of my major gripes with TRT.
I do injections every 3.5 days. Monday morning and Thursday morning. But the 3 times a week. I wonder if doing 3 times a week is a good idea. So you kind of do morning then for your second afternoon, then your 3rd late at night?
 
Yes. That gives me a fairly balanced timing schedule for my doses.

If I have learned nothing else from TRT is that EVERYONE needs to find the protocol that works for them.

If you are lucky enough to good for a starting protocol...that’s great. But to truly get “dialed in” seems to take a lot of adjusting.

And then you have to be patient to see if what you changed works better or worse. Then repeat.
 
Yes. That gives me a fairly balanced timing schedule for my doses.

If I have learned nothing else from TRT is that EVERYONE needs to find the protocol that works for them.

If you are lucky enough to good for a starting protocol...that’s great. But to truly get “dialed in” seems to take a lot of adjusting.

And then you have to be patient to see if what you changed works better or worse. Then repeat.
Yeah it’s really a pain in the ass. I am trying to get to the point where I don’t need an AI. Because every time I take it, I just go into a deep hole
 
Yes, I only took three, .125mg doses and thought I was dying. Never again.

I would try small, more frequent doses of T. Stop the AI.

Good luck.
 

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⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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