Nelson Vergel
Founder, ExcelMale.com
Sometimes people who use blood pressure drugs become a little fitter and stronger. Some - not all - blood pressure drugs seem to inhibit the break down of muscle tissue as well. Danish researchers, who studied the effect of blood pressure medication losartan on the muscles in healthy men, have found out the mechanism behind the muscle-strengthening effect of this drug: losartan is a myostatin inhibitor.
Conclusion
"This is the first study to investigate the potential of blocking the AT1R to modulate the response of skeletal muscle to exercise in humans", the researchers wrote. "We found no influence of this medication on the response of satellite cells or on a broad panel of muscle and connective tissue-related genes. However, we did observe a greater suppression of myostatin with losartan ingestion, which, if confirmed, could have beneficial effects on aging muscle undergoing hypertrophy in response to heavy resistance trainings."
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Conclusion
"This is the first study to investigate the potential of blocking the AT1R to modulate the response of skeletal muscle to exercise in humans", the researchers wrote. "We found no influence of this medication on the response of satellite cells or on a broad panel of muscle and connective tissue-related genes. However, we did observe a greater suppression of myostatin with losartan ingestion, which, if confirmed, could have beneficial effects on aging muscle undergoing hypertrophy in response to heavy resistance trainings."
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