A Pain That’s Hard to Discuss

Nelson Vergel

Founder, ExcelMale.com
Anal fissures are not exactly a topic for ****tail party conversation, and the reluctance to discuss them often leaves sufferers thinking they are the only ones affected.
In fact, this potentially painful, debilitating, anxiety-provoking condition is quite common. If a fissure doesn’t heal on its own, it can usually be treated and recurrences prevented with conservative measures.
“Most people don’t know they exist because nobody wants to talk about them,” Emma Rushton of Nashville, said in an email that urged me to write about the treatment and prevention of these tiny tears in the anal opening. “Believe me, when I was struck down by mine, the last thing I wanted to do was tell people.

http://well.blogs.nytimes.com/2013/11/18/a-pain-thats-hard-to-discuss/?_r=0
 
BOTULINUM TOXIN (BOTOX®) INJECTION

Botulinum toxin is injected directly into the internal anal sphincter muscle to promote anal sphincter relaxation and subsequent healing. This injection results in full healing in approximately 50-80% of patients. Injections are performed as an outpatient, same-day surgery procedure and, occasionally, can be performed in the office setting. Recurrences may occur in up to 40% of patients, but patients may be re-injected with good rates of fissure healing. Patients in whom Botulinum toxin injection fails are often recommended for traditional surgical sphincterotomy.

https://www.fascrs.org/patients/disease-condition/anal-fissure-expanded-information
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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