200mg compounded cream, $$

No doubt your E2 was very low then. I'd add maybe HCG or highe dose DHEA&Preg

One more thing, were you applying 200mg twice a day like BK asked? or 100mg x2 a day

200mg 2x a day. And yes, I suspect free E2 is low. I've been experiencing penile shrinkage, stiff joints, and other unpleasant things. Nothing like high E2.
 
If you can get a script call EmpowerRx and get the compounded T cream from them if you in the US........ Waaaaaaaaaaaaaaaaaaay cheaper and most likely better quality ingredients...

I called EmpowerRx this morning --- sent them a copy of the script. Apparently, they can't do it. They only have the TopiClick and no where near the dose I take (400mg / day).
 
I called EmpowerRx this morning --- sent them a copy of the script. Apparently, they can't do it. They only have the TopiClick and no where near the dose I take (400mg / day).

Why can't you do TopiClick, it's better. Way easier to measure. You apply 4 clicks a day on your scrotum twice a day, it'll be 400mg
 
Why can't you do TopiClick, it's better. Way easier to measure. You apply 4 clicks a day on your scrotum twice a day, it'll be 400mg

I started out with the TopiClick, but 4 clicks didn't seem to yield enough cream. 1g from the tube I have is about 3-4 times more than 4 clicks, but it only lasts 3-4 weeks and costs $339. The bigger issue here is that I'm under rather incompetent care. The doctor is a gynecologist over 85. When I told him my libido is lower now than before starting T therapy, his response was "maybe T therapy isn't for you". Not quite the thing you want to hear when you're trying to solve a hormone problem.
 
Shouldn't 2g from the tube per day last 45 days? Still expensive though. Do you think your tube is underfilled?

Edit: Also if you're spending $300 per month on the cream, can you drop another $50 and get a quick E2 sensitive test or are you in a location without access to ordering that test?
 
Shouldn't 2g from the tube per day last 45 days? Still expensive though. Do you think your tube is underfilled?

Edit: Also if you're spending $300 per month on the cream, can you drop another $50 and get a quick E2 sensitive test or are you in a location without access to ordering that test?

My thoughts exactly. They are underfilling the tube on purpose and charging extra for it. It's too bad EmpowerRx doesn't having anything of that strength (they declined to send me a quote).

Yes to the Sensitive E2 test. Been wanting to do it for a while, but it's hard to break away to the lab during business hours. Will do it soon.
 

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HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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