2 weeks into new TRT protocol, and...

FrankUnderwood

New Member
I had previously tried a multi-month Clomid restart that gave me some good days punctuated with very bad days(mood swings, acne, irritability, etc). After the cessation of the restart protocol, my levels crashed a bit lower than they were pre-clomid.

Im now exactly 2 weeks into my new TRT regimen with Defy on a Monday morning/Thursday evening Test-Cyp/HCG schedule and I cannot begin to explain how transformative this treatment is already making me feel, even though we are at the very early stages of what likely will be a life-long marathon.

I went to work, as in physically visited my office Wednesday afternoon, for the first time in many weeks and put in a solid 4 hours of work. Thursday, I was in the office all day and was able to work and attack problems like I haven't been able to in many many months. My mood is extremely positive, so much so that my wife asked me if I was sleeping with someone on the side (side note, id historically exhibit great moods after sex but it only lasted 24 hrs and then back to the dumps i went...). I laughed, said no, why would you ask? "This entire week you have been happier than Ive seen you in months. Smiling, laughing, conversing. And we haven't had sex in over a week!" My sleep quality is also markedly improved, yet I don't feel the need to take my melatonin. Initially she was concerned with my protocol change, having been inundated with the negative views of testosterone and stories of roid-rage from the media. Her comments now are a complete 180.

I realize its still early days, but am hoping/praying that this positive trend continues to the 4th/6th week and beyond. I feel like some significant mental/emotional/physical clouds are parting, and am truly appreciative of the efforts of Dr Saya and Dr Crisler and the rest of the fine folks at Defy.
 
That's awesome - congratulations!

I agree on the work productivity angle. When I've been at what I feel are optimal test levels, I'm a machine at work - cranking out deliverables...very high productivity. When I'm at low-T levels, I find I'm not productive, not motivated, and generally not as good a "thinker" and not as creative.

Since I'm a self-employed consultant - Low-T directly impacts my income, not just my well being and general health.

Glad to hear early success with Defy - I start with them next week!
 
I had previously tried a multi-month Clomid restart that gave me some good days punctuated with very bad days(mood swings, acne, irritability, etc). After the cessation of the restart protocol, my levels crashed a bit lower than they were pre-clomid.

Im now exactly 2 weeks into my new TRT regimen with Defy on a Monday morning/Thursday evening Test-Cyp/HCG schedule and I cannot begin to explain how transformative this treatment is already making me feel, even though we are at the very early stages of what likely will be a life-long marathon.

I went to work, as in physically visited my office Wednesday afternoon, for the first time in many weeks and put in a solid 4 hours of work. Thursday, I was in the office all day and was able to work and attack problems like I haven't been able to in many many months. My mood is extremely positive, so much so that my wife asked me if I was sleeping with someone on the side (side note, id historically exhibit great moods after sex but it only lasted 24 hrs and then back to the dumps i went...). I laughed, said no, why would you ask? "This entire week you have been happier than Ive seen you in months. Smiling, laughing, conversing. And we haven't had sex in over a week!" My sleep quality is also markedly improved, yet I don't feel the need to take my melatonin. Initially she was concerned with my protocol change, having been inundated with the negative views of testosterone and stories of roid-rage from the media. Her comments now are a complete 180.

I realize its still early days, but am hoping/praying that this positive trend continues to the 4th/6th week and beyond. I feel like some significant mental/emotional/physical clouds are parting, and am truly appreciative of the efforts of Dr Saya and Dr Crisler and the rest of the fine folks at Defy.

You have a real interesting story. Do you have an update on your condition?
 
You have a real interesting story. Do you have an update on your condition?

apologies, missed your question.

current update - I'm now in week 6 and feel fantastic. still taking my shots monday morning/thursday evening. my weight is up 8 lbs, but I'm attributing that to a relaxed carb-filled diet on a spring break trip with my family. the weight is slowly coming back down. my facial skin is a bit oilier now and i have had one or two pimples. i am using face soap and wipes that both contain 2% salicylic acid. i might try out nizoral soap to try to combat the light acne.

time wise im halfway to the 12 week point where we will re-draw labs and check numbers.

feelings wise - fantastic mood that lasts for days, morning wood, solid strong boners (although my ejaculate seems to be a bit less than before), a sex drive that my wife is taking advantage of 4X weekly, and I'm not feeling smashed after my workouts. i have changed nothing in my diet or training regimen outside of beginning my treatment. i am kicking absolute ass at work which folks are glad to see. it reminds my boss and colleagues of my performance 5+ yrs ago before my decline.

so far, so good! will continue to report progress!
 
apologies, missed your question.

current update - I'm now in week 6 and feel fantastic. still taking my shots monday morning/thursday evening. my weight is up 8 lbs, but I'm attributing that to a relaxed carb-filled diet on a spring break trip with my family. the weight is slowly coming back down. my facial skin is a bit oilier now and i have had one or two pimples. i am using face soap and wipes that both contain 2% salicylic acid. i might try out nizoral soap to try to combat the light acne.

time wise im halfway to the 12 week point where we will re-draw labs and check numbers.

feelings wise - fantastic mood that lasts for days, morning wood, solid strong boners (although my ejaculate seems to be a bit less than before), a sex drive that my wife is taking advantage of 4X weekly, and I'm not feeling smashed after my workouts. i have changed nothing in my diet or training regimen outside of beginning my treatment. i am kicking absolute ass at work which folks are glad to see. it reminds my boss and colleagues of my performance 5+ yrs ago before my decline.

so far, so good! will continue to report progress!

Great to hear. What is your protocol? Dosing?
 

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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