Hello All,
First, thank you all for you knowledge throughout the years, it has certainly helped. I have used this forum often in the past for questions on topics and I appreciate it. I have never had to post as most of the answers were located in the threads on here, so I will try to make this short for review.
Backstory- Have been on TRT due to cancer since 2015, with generally decent results overall. Over the past 8-12 months, I have been having extreme libido issues, as in zero libido. Protocol was 0.2mL (200mg/mL) every 3 days, which usually put me in the 800-850 TT range (and has been for the past 6 years or so). Labs looked good, so I thought, maybe I need to increase my dose. Doc put me on 0.3mL (200 mg/mL) twice a week, or 0.6mL a week. Unfortunately no change, besides maybe some better gym gains. Other symptoms- motivation slightly less and not quite as much energy. Performance from an intimacy aspect not really an issue, just the drive. Upcoming endo appointment in June.
Supplements- L-Dopa (recent), L-Tyrosine (recent), MV, calcium, DIM (recent). Started the L-Dopa & Tyro as I thought maybe a dopamine issue. No changes but some more energy. No other meds that cause libido side effects.
Rule out- I have tried to rule out everything possible, both with the help of docs and ordering labs myself. Saw a psych and sex therapist just in case, nothing that they could identify. I also do not drink, smoke or anything else recreational. Lifestyle wise, no issues or abnormal stressors and I workout 3-4 times a week.
Labs- These are all recent labs, within the past 30 days.
CBC- all normal
CMP- all normal
Lipid- HDL a little low at 34 and LDL a little high
A1C- 5.3 normal
Total T- 1265
Free T- 27.1 (8.7-25.1)
SHBG- 38.4 (16.5-55.9)
E2- 25 (11-44) 4/8/25
DHEA- 203 (89-427)
FT3/FT4/TSH- normal
PSA- normal
Cortisol Random- 10.6 (no ref)
Prolactin- 8.0 (4.0-26)
IFG1- 164 (72-228)
HGH- 3.82 (<2.47)
That's where I am so far and completely stumped. Besides libido, I overall feel well, but I have no idea why it just gradually disappeared. I'm also curious why my HGH would be elevated, but maybe it was random. I looked through other discussions and felt like this one was different, so I apologize if it seems repetitive to another. Open to any suggestions or ideas that y'all may have. Thanks in advance.
First, thank you all for you knowledge throughout the years, it has certainly helped. I have used this forum often in the past for questions on topics and I appreciate it. I have never had to post as most of the answers were located in the threads on here, so I will try to make this short for review.
Backstory- Have been on TRT due to cancer since 2015, with generally decent results overall. Over the past 8-12 months, I have been having extreme libido issues, as in zero libido. Protocol was 0.2mL (200mg/mL) every 3 days, which usually put me in the 800-850 TT range (and has been for the past 6 years or so). Labs looked good, so I thought, maybe I need to increase my dose. Doc put me on 0.3mL (200 mg/mL) twice a week, or 0.6mL a week. Unfortunately no change, besides maybe some better gym gains. Other symptoms- motivation slightly less and not quite as much energy. Performance from an intimacy aspect not really an issue, just the drive. Upcoming endo appointment in June.
Supplements- L-Dopa (recent), L-Tyrosine (recent), MV, calcium, DIM (recent). Started the L-Dopa & Tyro as I thought maybe a dopamine issue. No changes but some more energy. No other meds that cause libido side effects.
Rule out- I have tried to rule out everything possible, both with the help of docs and ordering labs myself. Saw a psych and sex therapist just in case, nothing that they could identify. I also do not drink, smoke or anything else recreational. Lifestyle wise, no issues or abnormal stressors and I workout 3-4 times a week.
Labs- These are all recent labs, within the past 30 days.
CBC- all normal
CMP- all normal
Lipid- HDL a little low at 34 and LDL a little high
A1C- 5.3 normal
Total T- 1265
Free T- 27.1 (8.7-25.1)
SHBG- 38.4 (16.5-55.9)
E2- 25 (11-44) 4/8/25
DHEA- 203 (89-427)
FT3/FT4/TSH- normal
PSA- normal
Cortisol Random- 10.6 (no ref)
Prolactin- 8.0 (4.0-26)
IFG1- 164 (72-228)
HGH- 3.82 (<2.47)
That's where I am so far and completely stumped. Besides libido, I overall feel well, but I have no idea why it just gradually disappeared. I'm also curious why my HGH would be elevated, but maybe it was random. I looked through other discussions and felt like this one was different, so I apologize if it seems repetitive to another. Open to any suggestions or ideas that y'all may have. Thanks in advance.
