obesity

  1. madman

    How GLP-1 Drugs Help Your Whole Body

    Ozempic and similar medications have received widespread attention for the treatment of diabetes and weight loss. There’s also growing research that they may help treat heart disease, sleep apnea, kidney disease, substance use disorder and other conditions. Demand has surged for the medications...
  2. madman

    Testosterone Therapy and Erythrocytosis: Unveiling Risks with SGLT2 Inhibitors and Metabolic Syndrome

    * Venesection is not recommended except for clonal erythrocytosis, due to its potential pro-thrombotic effects. * Repeated venesection can lead to decreased tissue oxygen pressure (pO2) and depletion of iron stores; factors which activate biological pathways that may paradoxically promote the...
  3. madman

    Reference intervals for serum TT, FT and SHBG in middle-aged men; the impact of overweight and obesity

    * Reference intervals for 216 men aged 45-65 years with a BMI <25 kg/m2 were 8.3 – 28.7 nmol/l for TT, 139 – 422 pmol/l for FT, and 17.7 – 80.8 nmol/l for SHBG. As BMI increases, a greater proportion of men fall below the lower limit of the reference intervals. Specifically, among men with a BMI...
  4. madman

    Beyond Blood Sugar: GLP-1 Receptor Agonists as a Multifaceted Therapy for Testosterone, Erectile Function, and Metabolic Outcomes in Men with Obesity

    * Given emerging data on sarcopenia and GLP-1 RAs, future studies should investigate the potential role of combined GLP-1 and testosterone therapies to optimize outcomes in body composition, metabolic control, and sexual health. Table 1. Impact of GLP-1 Receptor Agonist Therapy on...
  5. madman

    Impact of GLP-1 receptor agonists on testosterone levels and men’s health

    https://www.urologytimes.com/view/pearls-perspectives-urology-role-in-glp-1-ra-treatments-with-hossein-sadeghi-nejad-md-and-nathalie-eid-ba In this 2-part episode of Pearls and Perspectives from the American Urological Association's (AUA) 2025 Annual Meeting in Las Vegas, NV, host Amy Pearlman...
  6. madman

    Novo Nordisk scores major legal win that bars many compounded versions of Wegovy, Ozempic

    https://www.cnbc.com/2025/04/25/novo-nordisk-legal-win-bars-many-compounded-wegovy-ozempic-drugs.html Key Points Novo Nordisk scored a huge legal victory that largely restricts compounding pharmacies from marketing or selling cheaper, unapproved versions of the drugmaker’s blockbuster weight...
  7. Nelson Vergel

    Empower Pharmacy CEO Shaun Noorian Challenges Big Pharma Over GLP-1 Drug Access and Pricing

    Everyone is talking about GLP-1s. As these so-called "miracle drugs" for weight loss exploded in popularity, shortages quickly followed. That’s when compounding pharmacies stepped in, offering lower-cost, customizable versions of these medications. But are patients really getting the same...
  8. madman

    Enhancing Primary Care Confidence in Managing Obstructive Sleep Apnea in Patients With Comorbidities

    Did you know that primary care clinicians are in the perfect position to identify and even manage obstructive sleep apnea (OSA)?
  9. madman

    The Link Between TRT and Obstructive Sleep Apnea: A Risk Factor Analysis

    * Our findings suggest that the presence of OSA risk factors may alter the effect of TRT on OSA incidence, where TRT is associated with lower incidence in people without risk factors and higher incidence in people with risk factors. INCIDENCE OF OBSTRUCTIVE SLEEP APNEA IN PATIENTS TAKING...
  10. madman

    GLP-1 Drugs Might Cut Dementia Risk in Half

    New evidence brings more good news about the unanticipated effects of the GLP-1 receptor agonists.
  11. madman

    FDA-Approved vs. Compounded GLP-1s: Comparing Safety, Quality, and Transparency

    The guest speakers says it all LOL! The Obesity Society (TOS) convened a panel of leading experts in obesity medicine, pharmacy, and regulatory law on March 19, 2025, to discuss the growing concerns surrounding the use of compounded GLP-1s for weight management and diabetes treatment. The...
  12. Pacman

    Tirzepatide: additives, alternative sources, and how to deal with the ban?

    I just found out about the whole ban on compounded tirzepatide (I been living under a rock apparently). My provider presents these options to me now: Empower Pharmacy (Tirzepatide/Niacinamide) Strive (Tirzepatide/Glycine/B12) Southend Pharmacy (Tirzepatide/B6) Red Rock (Tirzepatide/Glycine) I...
  13. madman

    Weight Loss Doctor Explains the Unexpected Benefit of Ozempic

    In this episode, Dr. Rena Malik, MD, and Dr. Alexandra Sowa dive into the transformative effects of new obesity medications, highlighting dramatic weight loss results and their profound impact on personal and romantic relationships. They explore both the psychological and social dimensions...
  14. madman

    Obstructive Sleep Apnea: Treatment Options for the Patient Struggling with CPAP

    Johns Hopkins sleep surgeon and airway specialist Kevin Motz will discuss the newest medical and surgical options for patients with obstructive sleep apnea (OSA) who struggle with using a continuous positive airway pressure (CPAP) machine.
  15. madman

    Exploring New Horizons in Incretin Therapy for Diabetes and Weight Loss

    In this episode, hosts discuss the efficacy of MariTide for obesity, a head-to-head comparison of semaglutide vs. tirzepatide, and concerns about GLP-1 agonist compounding. https://www.hcplive.com/view/diabetes-dialogue-exploring-new-horizons-in-incretin-therapy-for-diabetes-and-weight-loss...
  16. madman

    Benefits of GLP-1 therapy for sleep apnea

    SURMOUNT-OSA Results: 'Impressive' in Improving Sleep Apnea Drs Akshay Jain and James Kim discuss the benefits of GLP-1 therapy for sleep apnea, as reported from the SURMOUNT-OSA trial. Key Insights from the Surmount OSA Study: Implications for Primary Care and Endocrinology Introduction Dr...
  17. madman

    Pharma-cise™ in the Glucagon-like Peptide-1 Receptor Agonists Era

    Ross Arena, PhD, Professor and Head of the Department of Physical Therapy, College of Applied Health Sciences, at the University of Illinois at Chicago, reviews his article appearing in the December 2024 issue of Mayo Clinic Proceedings, where he finds promise in the newly emerging medical...
  18. madman

    Cup o'Joe-New Weight Loss Drugs In The Works!

    Ozempic, Wegovy and Mounjaro are turning out to be some of the most successful drugs ever churned out by pharmaceutical companies. That’s because when it comes to treating type 2 diabetes and causing weight loss, they really do work. Sales are set to soar to even greater heights because...
  19. madman

    Anti-obesity Medications: Considerations around Compounding

    We hosted a Virtual Science Writers Conference to address the surging demand for a new generation of highly effective anti-obesity medications is creating interest in compounded versions of these medications. Society experts discussed the importance of prescribing FDA-approved medications to...
  20. madman

    LPCN 2401 for Obesity Management Clinical Study Results

  21. madman

    LPCN 2401 for Improved Body Composition in Obesity Management

    https://lifescievents.com/event/lipocine/
  22. madman

    Story of A Pioneer in Obesity Care

  23. madman

    The Golden Era of GLP-1 Drugs

    Chapters: 0:00—Introduction to GLP-1 Drugs 08:48—Obesity as a Major Health Concern 11:52—Diabetes: The Original Indication for GLP-1 15:26—Cardiovascular Implications of GLP-1 20:16—Kidney Health and GLP-1 Mechanisms 24:02—Exploring GLP-1 Effects on Mental Health 29:27—Challenges and Side...
  24. madman

    “Weighing In” on GLP-1 Receptor Agonists for People With HIV

    Presenter: Suman Srinivasa, MD, MS The IAS–USA Annual Update on HIV Management in Chicago, Illinois May 16, 2024 Harnessing GLP-1 Receptor Agonists for Weight Management in HIV Patients: Insights from Dr. Suman Shrinivasa In a highly anticipated session, Dr. Suman Shrinivasa, Assistant...
  25. madman

    Pioneering study - how GLP-1 therapy combined with KYZATREX® impacts muscle mass and energy levels in male patients undergoing weight loss

    https://www.prnewswire.com/news-releases/nubioage-nuhx-and-marius-pharmaceuticals-team-up-for-collaborative-glp-1-comparison-study-in-male-patients-302257781.html WEST PALM BEACH, Fla., Sept. 25, 2024 /PRNewswire/ -- nuBioAge, a longevity science and wellness network based in West Palm Beach...
  26. madman

    TESTOSTERONE LEVELS IN OBESE PATIENTS: THE ROLE OF OBSTRUCTIVE SLEEP APNEA

    Objectives An association between Obstructive Sleep Apnea (OSA) and gonadal dysfunction is known. Specifically, while obesity is commonly associated with reduced testosterone secretion, some studies suggest OSA can independently affect testosterone. Moreover, although most studies show that...
  27. madman

    One of the leading figures in research and scientific discovery regarding testosterone and diabetes

    Dr. Dandona! *Time doesn’t slow down Dandona. At age eighty, he still conducts two full clinics a week, where he and his fellows see twenty-five to thirty patients. How does he do it? That’s the question we want to ask...
  28. madman

    Management of male obesity-related secondary hypogonadism

    Core Tip: The obesity pandemic has increased the prevalence of obesity-related health morbidities including male obesity related secondary hypogonadism (MOSH). Although weight loss is the ideal therapeutic option for MOSH, testosterone replacement therapy (TRT) is often necessary because of the...
  29. madman

    TRT for hypogonadism: A primer for primary care

    Abstract Testosterone replacement therapy (TRT) is a crucial intervention for men diagnosed with hypogonadism,a condition characterized by inadequate testosterone production. As primary care NPs play an essential role in managing patients with hypogonadism, they must comprehensively understand...
  30. madman

    The link between diabetes and low testosterone in men

    In this first edition of The MCCRC Podcast, Dr. Kim Kuebler sits down with Dr. Julian L. Gallegos to talk about T2DM, Obesity, and Hypogonadism.
  31. madman

    Could Popular Weight Loss Drugs Help Prevent Cancer?

    In this episode, Dr. Diane Reidy-Lagunes sits down with MSK’s Dr. Neil Iyengar, a nationally recognized expert on the relationship between obesity, metabolic health, and cancer. Together, they discuss the intriguing connection between a new class of weight loss drugs, called GLP-1 agonists, and...
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