cvd

  1. madman

    Cardiovascular disrupting effects of bisphenols, phthalates, and parabens related to endothelial dysfunction

    ABSTRACT Cardiovascular diseases (CVDs) are the leading cause of death worldwide. CVDs are promoted by the accumulation of lipids and immune cells in the endothelial space resulting in endothelial dysfunction. Endothelial cells are important components of the vascular endothelium, that regulate...
  2. madman

    High Testosterone Levels: Impact on the Heart

    Abstract Testosterone, the main endogenous active androgen, is used to treat many clinical conditions, such as hypogonadism, infertility, erectile dysfunction, osteoporosis, anemia, and in transgender therapy (female-to-male transsexuals). Androgens are also used by athletes to enhance...
  3. madman

    From Taboo to Treatment: Changing the Conversation on Male Sexual Dysfunction

    In my latest podcast episode with Dr. Mohit Khera, M.B.A., M.P.H., a world-renowned urologist with expertise in sexual medicine and testosterone therapy, we dive deep into the realm of male sexual health. I'm honored to host Dr. Mohit Khera, a world-renowned expert on male sexual dysfunction...
  4. madman

    Testosterone Therapy and the Risk of Cardiovascular Disease

    Abstract The debate over the cardiovascular (CV) implications of testosterone therapy (TT) have resulted in diverging safety recommendations and clinical guidelines worldwide. This narrative review synthesizes and critically evaluates long-term studies examining the effects of TT within the...
  5. madman

    Do statins decrease testosterone in men?

    https://intbrazjurol.com.br/vol-numbers-41-50/vol-50-n-02-2024/ 119 | Do statins decrease testosterone in men? Systematic review and meta-analysis Felipe Placco Araujo Glina, Leonardo Lopes, Rodrigo Spinola e Silva, Eduardo Augusto Correa Barros, Bruno Biselli, Sidney Glina [View Full...
  6. madman

    Men's Sexual Function (and Dysfunction)

    https://www.vumedi.com/channel/nyu-langone/tab/annual-focus-on-mens-health-2023/video/focus-on-mens-health-2023-mens-sexual-function-and-dysfunction/ https://www.hsadeghi.com/dr-sadeghi/ Dr. Sadeghi-Nejad is Professor of Urology and Obstetrics & Gynecology/Director of Men’s Health at...
  7. madman

    High Testosterone Blood Levels May Increase Mortality

    https://academic.oup.com/jsm/article/21/Supplement_1/qdae001.281/7600971 Abstract Introduction The benefits and risks of testosterone therapy (TT) have been a subject of long-standing debate. The recent TRAVERSE trial demonstrated that men who received TT did not show an increased risk of...
  8. madman

    Impact of TRT on Adverse Cardiovascular Events in Men with Low Testostosterone: Evaluation of Physiological and Supraphysiological T Levels

    https://academic.oup.com/jsm/article/21/Supplement_1/qdae001.084/7600775 Abstract Introduction Sustained treatment with elevated levels of exogenous testosterone (T) has been linked to various adverse events, particularly concerning cardiovascular risks. However, there is currently a lack of...
  9. madman

    Evaluation of the Male with Erectile Dysfunction

    37.1 Introduction The evaluation of the male who presents with erectile dysfunction (ED) can be one the most impactful visits in the long-term health of the patient. As illustrated in this chapter, ED has a number of important implications for overall men’s health. ED may be the only symptom...
  10. madman

    Molecular Biology and Physiology of Erectile Function and Dysfunction

    36.1 Introduction Erectile dysfunction (ED) refers to the inability to achieve or maintain an erection for satisfactory sexual performance. It is highly prevalent among aging men and can have a significant impact on quality of life and interpersonal relationships [1]. It was estimated in 2000...
  11. madman

    Menopause and Estrogen

    On this episode, Dr. Sadaf Lodhi is joined by renowned Medical Oncologist, Dr. Avrum Bluming to discuss everything you need to know about menopause and estrogen. From the need for sex-specific research in medicine to common misconceptions, this episode dives deep into the significant steps being...
  12. madman

    Estrogen and cardiovascular disease in women

    Abstract A large body of scientific research accumulated over the past twenty years documents the cardiovascular (CV) benefits of estradiol (E2) and progesterone (P4) in reproductive-aged women. In contrast, accelerated development of CV disease (CVD) occurs in the absence of ovarian-produced...
  13. madman

    The Most Exciting Time for Testosterone - TRAVERSE Results 4 Studies

    https://www.medscape.com/viewarticle/999636?form=fpf Rachel S. Rubin, MD: I am Dr Rachel Rubin, urologist and sexual medicine specialist in the Washington, DC, area. I am so blessed to have with me one of my favorite sexual medicine doctors on earth, Dr Mo Khera, professor of urology at...
  14. madman

    Is TRT safe in men who are at high risk for cardiovascular disease?

    Dr. Khera breaking it down! Is testosterone replacement therapy safe in men who are at high risk for cardiovascular disease? Ask a Sexpert! Dr. Mohit Khera explains this topic in our latest edition of this video series.
  15. madman

    PDE5 inhibitors (Cialis, Viagra, etc) and cardiac health: Princeton IV consensus guidelines:

    Been waiting on this one. Damn, that is deep! Abstract Background In 1999, 1 year after the approval of the first oral phosphodiesterase type 5 (PDE5) inhibitor for the treatment of erectile dysfunction(ED), the first Princeton Consensus Conference was held to address the clinical...
  16. madman

    The Safety Of Systemic Menopausal Hormone Therapy

  17. madman

    Associations Of T, DHT, Estradiol, And SHBG With All-cause And Cardiovascular Mortality

    Studies examining associations of circulating sex steroids with mortality risk in men show inconsistent results for testosterone (T), with limited data for dihydrotestosterone (DHT) and estradiol (E2). We aimed to clarify associations of sex steroids, sex hormone-binding globulin (SHBG), and...
  18. madman

    Clitoris color Doppler ultrasound - Female Sexual Dysfunction

    Clitoral Doppler ultrasound (CDU) is a noninvasive and easily applicable test used to assess the vascular patency and perfusion of clitoral arteries by measuring the rate of change in blood flow. Among hemodynamic parameters assessed during CDU, the pulsatility index (PI) is proposed to reflect...
  19. madman

    TRT on cardiovascular outcomes in hypogonadal men

    Abstract Objective To investigate the impact of testosterone replacement therapy (TRT) on cardiovascular outcomes in hypogonadal men. Methods A meta-analysis of 26 randomized controlled trials involving 10 941 participants was conducted. Various clinical outcomes, including all-cause...
  20. madman

    Dr. Khera highlights TRAVERSE trial of testosterone replacement therapy

    "So far, we have only 2 published, which is the cardiovascular results, which showed no increase in cardiovascular events, and the sexual function results, showing improvements in libido, but not erectile function, in up to 2 years," says Mohit Khera, MD, MBA, MPH...
  21. madman

    Navigating Erectile Dysfunction Together

    https://www.issm.info/meetings/issm-podcasts/issm-podcast-season-1-episode-21 In this episode, with Francesa Tripodi a sexologist, We delve into a pressing issue affecting many couples: Erectile Dysfunction (ED). We explore how ED, especially among men over 40, can strain relationships...
  22. madman

    Cardiovascular disease, osteoporosis and HRT

    This video features an interview with Professor Marco Gambacciani, a menopause specialist from Italy, discussing the importance of hormone replacement therapy (HRT) in reducing the risk of cardiovascular disease and osteoporosis in women. They highlight the lack of awareness and access to...
  23. madman

    Cardiovascular Safety of TRT

    https://www.sciencedirect.com/science/article/abs/pii/S0302283823031391?via%3Dihub Experts’ summary: Lincoff et al. conducted a multicenter, randomized, double-blind, placebo-controlled, noninferiority trial to evaluate the risk of cardiovascular and thromboembolic events with testosterone gel...
  24. madman

    Is ED an Independent Risk Factor or Risk Marker for CVD and What Is the Role of CT Calcium Scoring?

  25. madman

    Testosterone Replacement Therapy and CVD

    Abstract Purpose of Review The purpose of this review is to analyze the link between testosterone replacement therapy (TRT) and adverse cardiovascular (CV) events. Recent Findings A few published studies suggest a link between TRT and CV events. These studies contained flaws, and many...
  26. madman

    Are PDE-5 Inhibitors Cardioprotective?

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