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  1. madman

    Testosterone Controversies: Lessons Learned from TRAVERSE 2025

    * Miner emphasized that TRAVERSE has reshaped the safety narrative around testosterone replacement therapy (TRT), easing concerns about cardiovascular and prostate risks. Many men with hypogonadism—who often suffer from fatigue, mood changes, and depression—are now more open to discussing TRT as...
  2. madman

    The interplay of health and heart health on sexual function: understanding the impact of CVD on sexual dysfunction in men

    * Erectile dysfunction is a marker of underlying cardiac disease, but many doctors are just not asking! @Nelson Vergel This is powerful! 6:00-6:15 * You need to lose about 75% of the lumen of the coronary artery before you get your first cardiac symptom but if you lose even a small...
  3. madman

    Testosterone Replacement in Cardiac Patients and Sexual Health

    Prof. Dr. Omer Raheem Post-Myocardial Infraction TRT Conclusion
  4. madman

    Cardiovascular Pharmacotherapy & Male Sexual Function

    Prof. Dr. Mahmoud Tantawy
  5. madman

    Breakthrough Trial Shows Heart Screening Saves Lives in Men 60–64

    In this compelling episode, cardiologists John M. Mandrola, MD, and Axel Diederichsen, MD, PhD, discuss the groundbreaking findings of the Dancavas 2 trial presented at the European Society of Cardiology meeting. Building on the previous Dancavas 1 study, this new research investigates the...
  6. madman

    Erectile Dysfunction (ED) Causes &Treatments

    In this powerful episode of e-Health Matters, Dr Oskar is joined by Professor Geoff Hackett, leading expert in urology and sexual medicine, to discuss a topic that affects millions of men but is still surrounded by silence: erectile dysfunction (ED). What you’ll learn: What causes ED —...
  7. madman

    The role of testosterone in cardiovascular health: benefits and risks of replacement therapy

    * This paper examines testosterone’s dual role in the cardiovascular system. Low levels are linked to increased risks of heart failure (HF) and coronary artery disease (CAD), while testosterone replacement therapy (TRT) can improve heart function, exercise tolerance, and metabolic health...
  8. madman

    Sexual Health as a Vital Sign: What Erectile and Sexual Dysfunction Reveal About Overall Health

    Erectile and sexual dysfunction aren’t just about intimacy—they can be powerful indicators of your overall health. In this eye-opening discussion, renowned urologist Dr. Mohit Khera joins Dr. Jeffrey Albaugh, a board-certified Advanced Practice Urology Clinical Nurse Specialist who specializes...
  9. madman

    Heart Disease Risks in Women with PCOS: New Insights, Therapies, and Gaps in Research

    In this webinar, Dr. Licy Yanes Cardozo presents the heightened cardiovascular risks in women with PCOS, the mechanisms underlying these risks, current treatments available, potential new therapies, and the existing knowledge gaps in women's health research. Summary Complications of...
  10. madman

    Subcutaneous vs. Intramuscular Testosterone: Do Delivery Methods Affect Blood Health and Hematocrit Risk?

    * 100 patients were identified as first-time TRT users, with 50 in the subcutaneous group and 50 in the intramuscular group. There was no significant difference in age, pre-TRT testosterone levels, pre-TRT hematocrit levels, or post-TRT hematocrit levels. There was a significant difference in...
  11. madman

    Struggling with ED? Dr. Jeff Albaugh Breaks Down Causes, Treatments, and How to Take Back Control

    Great presentation! I have been stressing this numerous times over the years. ED is multifactorial and vascular issues are the most common cause. Stop getting caught up on T, DHT, estradiol let alone the myth that one needs high FT/DHT! T plays a small role. What about testosterone? *...
  12. madman

    Erectile dysfunction: A vital sign for cardiovascular health

    * The P4 panel recommendations confirm that ED is a strong, independent predictor of cardiac events, even when traditional risk factors such as cholesterol, diabetes and blood pressure are controlled for. In short, ED is the body's "check engine light" for heart disease. * Phosphodiesterase-5...
  13. madman

    Muscle Mass, Testosterone & Erections: The Doctor's Blueprint for Men’s Health

    * the best overall marker for overall health in men is ERECTILE FUNCTION * One of the most striking points from the discussion was Dr. Kohler’s perspective on erectile dysfunction (ED). He described it not just as a sexual problem, but as one of the earliest "check engine lights" for heart...
  14. madman

    Measuring Erections for Health and Longevity

    Unlock the secrets of male well-being with Christos Konstantinidis, the pioneering founder and CEO of Adam Health, as we unveil the profound link between erectile health and holistic male wellness. Discover how your body's signals, often overlooked, could be the earliest indicators of serious...
  15. madman

    Testosterone Therapy and Heart Health: Large Study Finds No Mortality Risk, But Raises Arrhythmia Concerns

    * our meta-analysis stands as the most up to date analysis restricted to RCTs directed to men aged 40 or older. * The main fndings were as follows: (1) there were no significant diferences between groups in all-cause mortality, cardiovascular mortality, MI, and stroke; (2) TRT signifcantly...
  16. madman

    How Oral Pills Testosterone (TRT) Work, Link to TRT & Prostate Cancer

    In this episode, Dr. Geo sits down with renowned urologist and men’s health expert Dr. Mohit Khera—professor at Baylor College of Medicine with over 160 peer-reviewed publications—to unpack the facts, myths, and future of testosterone treatment. They cover oral options, including Kyzatrex, how...
  17. madman

    Managing Erectile Dysfunction & Heart Health

    Dr. Dapo lluyomade * I think erectile dysfunction, we should really begin to think of erectile dysfunction as subclinical atherosclerosis until proven otherwise Is your patient’s sexual dysfunction an early indicator of serious cardiovascular disease? In this episode of BackTable Urology...
  18. madman

    Researchers Reveal the Alarming Long-Term Risks of Steroid Use

    Strength/limitations (see following post)! https://www.emjreviews.com/en-us/amj/cardiology/news/researchers-reveal-the-alarming-long-term-risks-of-steroid-use/ A LONG-TERM study conducted in Denmark has revealed that male users of anabolic androgenic steroids (AAS) face significantly...
  19. madman

    Cardiometabolic outcomes of early onset hypogonadism in males

    * Interpretation of the TRAVERSE findings is limited by several factors. Over 60 % of participants discontinued treatment prior to trial completion, resulting in a median exposure of less than 22 months. Additionally, outcome data were only available for approximately 80 % of the potential...
  20. madman

    Take Homes for Your Practice from Princeton 4: ED, CVD, and Sexual Function

    * PDE5 meds MAY reduce MI, Stroke & Mortality Take Homes for Your Practice from Princeton 4: ED, CVD, and Sexual Function - Martin Miner, MD and Noel N. Kim, PhD Members of the Princeton 4 Commitee
  21. madman

    Some of the biggest questions facing men’s health and urology today

    https://www.urologytimes.com/view/pearls-perspectives-helen-bernie-do-mph-at-aua-2025 In this episode of Pearls and Perspectives from Urology Times, host Amy Pearlman, MD, sits down with Helen Bernie, DO, MPH, at the American Urological Association's (AUA) 2025 Annual Meeting in Las Vegas for...
  22. madman

    Testosterone and Cardiovascular Risk: The TRAVERSE Trial and Results from the New FDA Label Change

    Mohit Khera, MD, MBA, MPH, Professor of Urology and F. Brantley Scott Chair of Urology, Baylor College of Medicine, Houston, Texas, discusses evolving understanding of testosterone therapy and cardiovascular risk. In this 13-minute presentation, Dr. Khera focuses on the pivotal TRAVERSE trial...
  23. madman

    Label change for testosterone: Implications for urologists, prescribers, and patients

    Key Takeaways The TRAVERSE trial showed testosterone therapy's MACE risk is non-inferior to placebo, reassuring prescribers and patients. Despite the updated labeling, caution is advised due to potential venous thromboembolic events, particularly pulmonary embolism. Experts anticipate guideline...
  24. madman

    Impact of Clomiphene Citrate Therapy on Lipid Profiles in Men with Hypogonadism

    * Labs collected include total testosterone (TT), free testosterone (fT), estradiol (E2), hematocrit (Hct), hemoglobin (Hg), triglycerides (TG), total cholesterol (TC), high density lipoproteins (HDL) and low density lipoproteins (LDL). Labs were collected before 11am, fasting, using LCMS and...
  25. madman

    It May Take 18 Months for Max Mood Enhancement Effects from TRT

    * Our findings suggest that mood improvements following TTh initiation may occur progressively, with the most substantial reductions in depressive symptoms observed after 18 weeks post-TTh initiation. TIMING OF MOOD IMPROVEMENT POST TESTOSTERONE THERAPY INITIATION Christian Corsini*, Edoardo...
  26. madman

    Hormonal Therapy and Thrombosis Risk With Testosterone

    https://www.vumedi.com/video/hormonal-therapy-and-thrombosis-risk-with-testosterone/
  27. madman

    From Phlebotomy to Formulation: Optimizing Hematocrit Control in Testosterone Therapy

    Briefing Document: Optimizing Hematocrit Control in Testosterone Therapy Source: Excerpts from "From Phlebotomy to Formulation: Optimizing Hematocrit Control in Testosterone Therapy - Excel Male TRT Forum" 1. Executive Summary Testosterone Replacement Therapy (TRT) offers significant benefits...
  28. madman

    Landon Trost, MD, on the impact of the FDA labeling changes for testosterone products

    This is key here! * "This now clarifies and substantiates the fact that there are not increased risks from a cardiovascular standpoint with [testosterone] therapy, at least at the doses studied," says Landon Trost, MD...
  29. madman

    Helen L. Bernie, DO, MPH, on the FDA’s labeling changes for testosterone products

    https://www.urologytimes.com/view/helen-l-bernie-do-mph-on-the-fda-s-labeling-changes-for-testosterone-products "I'm so excited about them finally removing this boxed warning," says Helen L. Bernie, DO, MPH. The FDA’s recent announcement of class-wide labeling changes for testosterone...
  30. madman

    John P. Mulhall, MD, shares his reaction to the FDA’s testosterone labeling changes

    * He added, “It is my hope that the AUA will, in short order, go back and change that statement, so that we now have guideline-based instructions to physicians that will say, you are now allowed to say to patients that testosterone therapy is not associated with major adverse cardiovascular...
  31. madman

    A Structured Review and Critical Analysis of RCTs on Nandrolone Decanoate's Cardiac Effects in Young Exercising Man

    ABSTRACT Aims The cardiovascular risks associated with anabolic-androgenic steroid (AAS) use, particularly nandrolone decanoate (ND), remain a topic of debate due to conflicting evidence from different types of studies. While observational research frequently reports adverse cardiac effects...
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