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As we close out Black History Month, we shine a necessary spotlight on a living legend whose name deserves to be spoken with the same weight as the breakthroughs he helped create. Dr. Arthur Burnett is a world-renowned urologist whose groundbreaking research around nitric oxide pathways helped...

* Substantial evidence suggests that sleep disorders may impair testosterone levels, partially improved after specific treatments (for instance: positive airway pressure for OSA). On the other hand, appropriate indications for testosterone replacement therapy (TRT) can alleviate hypogonadism...

How often should men on TRT check their hematocrit? The standard monitoring schedule includes a baseline CBC before starting TRT, a recheck at 3 to 6 weeks, another at 3 months, and then at 6 and 12 months once stable. Any dose or formulation change resets the monitoring clock, requiring a...

Dr. Peter Wilson I am going to give you some pearls from recent talks. 1:28-2:19 * Shehzad Basaria from Harvard who's on the TRAVERSE Trial. He said one of the biggest mistakes were making is assuming free testosterone is correct. Thats important and I think we in endocrinology and urology...

Take home message

Heart disease risk isn’t just about cholesterol. In this episode of A Whole New Level, Dr. Matthew Budoff explains why coronary artery calcium (CAC) scoring may be the most important test most people aren’t getting—and why imaging your arteries directly can reveal risk that blood tests alone can...

Diagnostic Assessment Strategy: Cardiovascular Risk & Systemic Health in Hypogonadal Patients 1. Strategic Framework for Cardiovascular Risk in the Hypogonadal Male In the contemporary clinical landscape, the management of the hypogonadal male demands a multi-modal assessment strategy that...

"Cardiometabolic Health: Do Sex Steroids Matter?" which looks at the role sex steroids play in cardiovascular health across the lifespan. Susan R. Davis My team who have contributed to the work presented Conclusions

* Chronic exposure to supraphysiologic doses of AAS induces a variety of pathophysiological changes in the cardiovascular system. The mechanisms are multifactorial, involving direct androgen receptor-mediated effects on cardiac and vascular tissues as well as indirect metabolic and hemodynamic...

* However, Mills argues that safety alone is not the benchmark for quality care. Men presenting with symptoms of low testosterone often have multiple comorbidities—poor sleep, sedentary lifestyle, suboptimal diet, or uncontrolled CV risk factors—that should be addressed alongside or even before...

* Finally, Bernie noted unresolved controversies in the field, including the optimal duration of fertility-preserving therapies, long-term outcomes of hybrid regimens combining testosterone with hCG, and best practices for sperm recovery after prolonged testosterone exposure. She emphasized the...

Listen closely here! 11:55-12:13 * you only need testosterone levels up for about 4-6 hrs in the day to produce an effect which works through the androgen receptor, the androgen receptor is present in every cell in the body so its not just a sex hormone it is a health hormone Another...

2025 American Heart Association Scientific Sessions Dr. Susan Davis * in the process of doing safety parameters, we found that when we gave women testosterone, we caused blood vessel dilation just like we saw when we gave women estrogen and in fact, when we gave women an ACUTE dose of...

Professor Michael Zitzmann We also know hematocrit can be increased by testosterone preparations. It depends on the preparation, and we think that there is data that shows that the threshold of 52-54% should not be surpassed, and men should be controlled for the hematocrit especially in the...

* Miner emphasized that TRAVERSE has reshaped the safety narrative around testosterone replacement therapy (TRT), easing concerns about cardiovascular and prostate risks. Many men with hypogonadism—who often suffer from fatigue, mood changes, and depression—are now more open to discussing TRT as...

* Erectile dysfunction is a marker of underlying cardiac disease, but many doctors are just not asking! @Nelson Vergel This is powerful! 6:00-6:15 * You need to lose about 75% of the lumen of the coronary artery before you get your first cardiac symptom but if you lose even a small...

Prof. Dr. Omer Raheem Post-Myocardial Infraction TRT Conclusion

Prof. Dr. Mahmoud Tantawy

In this compelling episode, cardiologists John M. Mandrola, MD, and Axel Diederichsen, MD, PhD, discuss the groundbreaking findings of the Dancavas 2 trial presented at the European Society of Cardiology meeting. Building on the previous Dancavas 1 study, this new research investigates the...

In this powerful episode of e-Health Matters, Dr Oskar is joined by Professor Geoff Hackett, leading expert in urology and sexual medicine, to discuss a topic that affects millions of men but is still surrounded by silence: erectile dysfunction (ED). What you’ll learn: What causes ED —...

* This paper examines testosterone’s dual role in the cardiovascular system. Low levels are linked to increased risks of heart failure (HF) and coronary artery disease (CAD), while testosterone replacement therapy (TRT) can improve heart function, exercise tolerance, and metabolic health...

Erectile and sexual dysfunction aren’t just about intimacy—they can be powerful indicators of your overall health. In this eye-opening discussion, renowned urologist Dr. Mohit Khera joins Dr. Jeffrey Albaugh, a board-certified Advanced Practice Urology Clinical Nurse Specialist who specializes...

In this webinar, Dr. Licy Yanes Cardozo presents the heightened cardiovascular risks in women with PCOS, the mechanisms underlying these risks, current treatments available, potential new therapies, and the existing knowledge gaps in women's health research. Summary Complications of...

* 100 patients were identified as first-time TRT users, with 50 in the subcutaneous group and 50 in the intramuscular group. There was no significant difference in age, pre-TRT testosterone levels, pre-TRT hematocrit levels, or post-TRT hematocrit levels. There was a significant difference in...

Great presentation! I have been stressing this numerous times over the years. ED is multifactorial and vascular issues are the most common cause. Stop getting caught up on T, DHT, estradiol let alone the myth that one needs high FT/DHT! T plays a small role. What about testosterone? *...

* The P4 panel recommendations confirm that ED is a strong, independent predictor of cardiac events, even when traditional risk factors such as cholesterol, diabetes and blood pressure are controlled for. In short, ED is the body's "check engine light" for heart disease. * Phosphodiesterase-5...

* the best overall marker for overall health in men is ERECTILE FUNCTION * One of the most striking points from the discussion was Dr. Kohler’s perspective on erectile dysfunction (ED). He described it not just as a sexual problem, but as one of the earliest "check engine lights" for heart...

Unlock the secrets of male well-being with Christos Konstantinidis, the pioneering founder and CEO of Adam Health, as we unveil the profound link between erectile health and holistic male wellness. Discover how your body's signals, often overlooked, could be the earliest indicators of serious...

* our meta-analysis stands as the most up to date analysis restricted to RCTs directed to men aged 40 or older. * The main fndings were as follows: (1) there were no significant diferences between groups in all-cause mortality, cardiovascular mortality, MI, and stroke; (2) TRT signifcantly...

In this episode, Dr. Geo sits down with renowned urologist and men’s health expert Dr. Mohit Khera—professor at Baylor College of Medicine with over 160 peer-reviewed publications—to unpack the facts, myths, and future of testosterone treatment. They cover oral options, including Kyzatrex, how...