brain

  1. Vince

    Muscle and less hidden abdominal fat are linked to a younger biological brain age.

    Scientists discovered that more muscle and less hidden abdominal fat are linked to a younger biological brain age. Deep visceral fat appeared to accelerate brain aging, while muscle mass offered a protective effect. https://www.sciencedaily.com/releases/2025/11/251125112506.htm...
  2. D

    Brain health with trt, missed sleep

    I (m, 37) take 20mg testosterone proprionate IM and 150 IU Hcg IM. I sometimes noticed under certain circumstances e.g. while travelling, that when I missed some sleep then the next day I didnt sleep really much more. And I just can go on and still look the same and dont feel too much tired or...
  3. Seagal

    SHBG --Access of plasma steroids to target tissues and cells

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064763/ "Access of plasma steroids to target tissues and cells While measurements of free steroid concentrations remain the most robust indicator of the biological activities of plasma steroids (Vermeulen et al. 1999), adoption of the free hormone...
  4. Seagal

    Testosterone and prosocial behavior

    https://www.nature.com/articles/s41386-023-01570-y
  5. D

    Lower E2 = Higher Memory Recall?

    Here is an interesting in vivo study with findings suggesting that lower levels of estrogen in the brain correlate to higher performance in varying forms of memory recall in men. @Cataceous @readalot @Nelson Vergel If a man were to experience brain fog and reduced memory recall while on TRT...
  6. J

    Anastrozole effects in the brain

    (Moving this to a new thread since it is a different topic) I am harping on this as I was doing pretty well on TRT with less than 100mg Testosterone Cypionate once a week plus 250IU HCG twice a week. Strong libido, good erections, etc. At that time, if I took 5mg cialis I could feel the effect...
  7. C

    Brain estrogen creation 'critical to maintain full sexual activity or desire in males'

    A tip of the hat to "PakMan" at PeakT for the reference to this article. The underlying work is on mice, but may have implications for humans. Summary: Researchers have uncovered specific regions of brain tissue where aromatase is present, that drives male sexual desire. Aromatase converts...
  8. S

    Oxaloacetate - reducing brain fog

    Anyone have any experience with Dave Asprey's products? I'm curious about his upgraded aging supplement: http://www.upgradedself.com/products/bulletproof-upgraded-aging-formula Looks like Oxaloacetate is the key ingredient.

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