brain

  1. Seagal

    SHBG --Access of plasma steroids to target tissues and cells

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064763/ "Access of plasma steroids to target tissues and cells While measurements of free steroid concentrations remain the most robust indicator of the biological activities of plasma steroids (Vermeulen et al. 1999), adoption of the free hormone...
  2. Seagal

    Testosterone and prosocial behavior

    https://www.nature.com/articles/s41386-023-01570-y
  3. D

    Lower E2 = Higher Memory Recall?

    Here is an interesting in vivo study with findings suggesting that lower levels of estrogen in the brain correlate to higher performance in varying forms of memory recall in men. @Cataceous @readalot @Nelson Vergel If a man were to experience brain fog and reduced memory recall while on TRT...
  4. J

    Anastrozole effects in the brain

    (Moving this to a new thread since it is a different topic) I am harping on this as I was doing pretty well on TRT with less than 100mg Testosterone Cypionate once a week plus 250IU HCG twice a week. Strong libido, good erections, etc. At that time, if I took 5mg cialis I could feel the effect...
  5. C

    Brain estrogen creation 'critical to maintain full sexual activity or desire in males'

    A tip of the hat to "PakMan" at PeakT for the reference to this article. The underlying work is on mice, but may have implications for humans. Summary: Researchers have uncovered specific regions of brain tissue where aromatase is present, that drives male sexual desire. Aromatase converts...
  6. S

    Oxaloacetate - reducing brain fog

    Anyone have any experience with Dave Asprey's products? I'm curious about his upgraded aging supplement: http://www.upgradedself.com/products/bulletproof-upgraded-aging-formula Looks like Oxaloacetate is the key ingredient.
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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