Injecting Testosterone Propionate on a Daily Basis

Jason Sypolt · Apr 19, 2017

After 6 months on daily T Cyp I felt that there was still a lot of room for improvement for me. I still just wasn't "feeling" it much. So I switched from Cypionate to Propionate. Having been on it for a couple of weeks now, I have a significantly higher/consistent energy level throughout the day. No afternoon slump and getting easily distracted like before. Libido seems a little higher too. I can't wait to get some tests in a few weeks and see what everything looks like.

I use a 30g 5/16 insulin syringe and inject 0.18mg every morning in abdomen or shoulders. It does not sting like I've read practically everywhere, maybe because of the small volume.

Anyone have similar or differing experiences, especially with SHBG on the lower end?

Vince · Apr 19, 2017

Jason thanks for starting this thread. I'm also interested in using propionate for my daily injection. What pharmacy and Clinic/doctor are you using and are you located in the USA.

Guided_by_Voices · Apr 19, 2017

I use prop also and inject from .1 to .12 per day. I have never used cyp for an extended period so I can't really compare, but I think prop is unfairly maligned. I started with prop because the short ester should make it much easier to get dialed in and if I overdid the dosage it should correct quickly, both of which have seemed to be true. Also it seems to have better reviews for sexual benefits. My SHGB is high so we are different in that regard, but my guess is that many who have a hard time getting to their sweet spot would have been better off starting with prop and then moving to cyp if there was some reason to, rather than starting with what IMO is the most complicated to get dialed in due to the difficulty in getting to a steady state based on symptoms. The only significant injection issues I've had happened when I injected into my leg, so I now inject the same as you.

Jason Sypolt · Apr 19, 2017

I don't inject in my legs much either. I can feel it more than shoulders and abdomen so I avoid legs when possible.

Vince, I'm in Ohio and a patient at Defy. I get everything from Empower and the Propionate comes as 100mg/ml in a 10ml vial. So I went from 20mg daily Cypionate to 18mg daily Propionate because there are a few more mg of T in the Propionate ester.

It has only been a couple of weeks, but I feel like I have the energy of my younger self right now. In the past, I was still tired and lethargic in the afternoon even with coffee. Now I'm sitting here (supposed to be writing code) and I'm ready to do anything and my mind is clear. It will be interesting to see what the tests reveal.

I guess even with these tiny changes I should probably wait a couple more weeks for everything to stabilize before I check.

mopes · Apr 19, 2017

Nice to see some accounts of daily prop use. Look forward to following along.

Vince Carter · Apr 19, 2017

Very interesting I'm listening in, a change has been on my mind, low SHBG and daily's already but had been thinking more with Enanthate than Prop.

Jason Sypolt · Apr 19, 2017

Vince Carter said:
Very interesting I'm listening in, a change has been on my mind, low SHBG and daily's already but had been thinking more with Enanthate than Prop.

Empower can also compound multiple esters together so that you get both slow and quick release.

Tom Larabee · Apr 19, 2017

I too am going to be following this one, as I have just started daily Test E last week and was wondering if Prop will help reduce my need for AI even more.

We are trying to do this without AI, hence the daily, but I am thinking after 2 months of this I might ask for Prop if my E numbers keep edging down but not enough.

I am really sensitive to AI's and can easily kill my E in a short period of time even on low dose once a week, so I am using DIM now and daily T.

Without Anastrazole my E edges up into the low 100's but I don't get symptoms other than greasy skin, and water weight. Using DIM we got it down some but not enough yet, so we are changing to daily T and increasing the DIM, so I will wait for the 2 months and see where it goes then and maybe ask to change to this if it continues to go down in 8 weeks.

CoastWatcher · Apr 19, 2017

After nearly two years on daily enanthate, I'm not interested in a change - I feel great and all is well balanced. But am fascinated with discovering how this plays out for others.

Vince · Apr 29, 2017

Hi Jason, I know it hasn't been very long. But I was wondering if there were any more updates on your daily injections of testosterone propionate?

Jason Sypolt · Apr 29, 2017

I am still doing good. I got my lab draw for a lot of tests on Tuesday, but I'm still waiting on the results for the hormone-related tests. My HCT dropped 1 point back to 47. I think I've already made up my mind that I don't want to go back to Cypionate, but I am still very interested in seeing all of the numbers. I will post a comparison once I get everything. Hopefully early next week.

user_joe · Apr 29, 2017

I think something interesting to see would be the different e2 numbers. I've read conflicting information. People will claim over and over that the ester does not effect aromitization, but if you follow people reporting on their steroid cycles they consistently report less water retention and need for ai with short esters. I had read that faster acting esters are more likely to convert to dht than e2. Considering results with gels and creams that could make sense. Daily prop "in theory" sounds like the way to go. Curious if you will have blood tests to compare.

Jason Sypolt · Apr 29, 2017

user_joe said:
I think something interesting to see would be the different e2 numbers. I've read conflicting information. People will claim over and over that the ester does not effect aromitization, but if you follow people reporting on their steroid cycles they consistently report less water retention and need for ai with short esters. I had read that faster acting esters are more likely to convert to dht than e2. Considering results with gels and creams that could make sense. Daily prop "in theory" sounds like the way to go. Curious if you will have blood tests to compare.

I have read that too. I didn't feel as though I had a lot of water retention on Cypionate, but my wedding ring is just a little more loose now. And I'm by no means muscular, but my arms look slightly more defined. So maybe there is some truth to that. Since the faster ester gets it in you quickly and then it's gone, maybe there is less time for aromatization and/or 5-ar. Whereas daily Cypionate keeps you at max levels up until you stop. So the testosterone is the same of course but the rate of delivery is quite different.

I have Total+Free T, E2, and DHT between daily Cypionate, daily Propionate, and bi-weekly Cypionate. It's not a direct compare because my Anastrozole dose was changed but will hopefully still be helpful.

Vince Carter · Apr 30, 2017

I've read that Prop will hit you harder (their words) because the short life of the ester but it's very closely the same mg of Test, which makes sense if you're using ~25 of Cyp it seems to be 24/48hrs to peak and then downward to the ~6 day half-life but Prop would peak much sooner in it's 2 days half-life.

Bud Black · May 1, 2017

Following as well...very interesting. Makes total sense if we could go daily to mimic natural system output.

Jason Sypolt · May 11, 2017

Sorry for the delay. LabCorp still does not have the Sensitive Estradiol results yet.

madman · May 11, 2017

Tom Larabee said:
I too am going to be following this one, as I have just started daily Test E last week and was wondering if Prop will help reduce my need for AI even more.

We are trying to do this without AI, hence the daily, but I am thinking after 2 months of this I might ask for Prop if my E numbers keep edging down but not enough.

I am really sensitive to AI's and can easily kill my E in a short period of time even on low dose once a week, so I am using DIM now and daily T.

Without Anastrazole my E edges up into the low 100's but I don't get symptoms other than greasy skin, and water weight. Using DIM we got it down some but not enough yet, so we are changing to daily T and increasing the DIM, so I will wait for the 2 months and see where it goes then and maybe ask to change to this if it continues to go down in 8 weeks.

Small daily doses of testosterone will aid in lowering e conversion in some, switching to prop daily low dose will not make much of a difference as prop ester is much faster acting and test levels spike faster which is more prone to e2 conversion albeit would only matter if one was injecting higher doses of prop. Suspension is notorious for aromatizing quickly as their is no ester and it hits the system quickest.

madman · May 11, 2017

Bud Black said:
Following as well...very interesting. Makes total sense if we could go daily to mimic natural system output.

Daily will be as close as you can get but you will never mirror the natural circadian rhythm with injectable as you will achieve a steady state with minor variations in peaks/valleys as oppose to the natural daily fluctuation of a healthy young male.

Jason Sypolt · May 14, 2017

Finally, the test results are back. Here is a comparison of lab results along with subjective changes. For reference, I am 38 years old. My SHBG is currently at 17.4 nmol/l, down from 21.9 last summer.

10/25/2016
- T Cyp 80mg every 3.5 days (Shallow IM, 1/2" 28g insulin syringe)
- Anastrozole/DIM 0.5mg/200mg every 3.5 days
- HCG 250IU every other day
- DHEA 25mg twice daily

Total Testosterone: 584 (348-1197)
Free Testosterone: 21.1 (8.7-25.1)
Estradiol LC/MS: 10.7 (8.0-35.0)
DHT: 41 (30-85)

Feels like I'm injecting water. Some weight loss with heavy cardio. Body fat is 26.9%. Minimal to no changes in muscle. Energy/libido start dropping around noon and gone by 5-6pm. Pretty bad acne on back and shoulders. The AI obviously crashed my E2, that certainly doesn't help things but I felt the exact same over the summer as when E2 was in the 20's and 30's, so that wasn't the determining factor for not really feeling anything. I do feel better than not on TRT though. I stopped the AI for a couple of months after seeing these results. Over last summer/fall I had also tried 60, 70, and 75mg BIW before being increased to 80mg BIW that you see in these results. Every time the dose went up, Total T would come out lower and lower.

12/08/2016
- T Cyp 20mg every day (Sub-Q, 5/16" 30g insulin syringe)
- HCG 250IU every other day
- DHEA 25mg twice daily

Total Testosterone: 999 (348-1197)
Free Testosterone: 22 (8.7-25.1)
Estradiol LC/MS: 39.4 (8.0-35.0)
DHT: 47 (30-85)

A little bit more energy. No change in libido. Not really tired until 2-3pm and then energy drops off pretty fast. Less body fat (23.3%) and some muscle definition starting to appear. Still have acne, sometimes down to my biceps. I went from wearing large to medium shirts. Free T % is actually much lower now, but this is a small improvement.

4/25/2017
- T Prop 18mg every day (Sub-Q, 5/16" 30g insulin syringe)
- Anastrozole 0.125mg every 3.5 days
- HCG 250IU every other day
- DHEA 25mg twice daily

Total Testosterone: 712 (348-1197)
Free Testosterone: 17.1 (8.7-25.1)
Estradiol LC/MS: 20.9 (8.0-35.0)
DHT: 28 (30-85)

My energy level has definitely increased and there is maybe a little libido increase. I feel a lot more alert. Energy level stays high until 10-11pm, and I don't tire nearly as quickly doing activities like yard work and exercise. I feel like this is more like my younger self. Acne better. Body fat is lower (19.7%) and muscle definition has increased. There is more of a visual change in body composition. Maybe there is some truth to the Cypionate ester causing bloat that I've seen mentioned occasionally. You look at the daily T Cyp results and think that should be a lot better going by the numbers, but that was not te case at all. I just felt numb on T Cyp, even when around 700-800 range.

I've searched all over for lab comparisons involving different esters for guys who just aren't feeling the benefits of TRT that others do. Hopefully this helps some people out who are looking for a comparison. By the way, injecting Propionate does not sting at all in the small amounts that I'm using.

For me though, this raises even more questions. I'm actually a bit surprised at the Propionate results and how Total/Free T are not higher given the faster absorption. I expected much higher FT. There is not a lot of SHBG to bind to, and it obviously isn't converting to DHT or Estradiol. DHT and Estradiol actually fell off a cliff. Albumin is normal. Where is the T going? Maybe I metabolize it so fast that BID injections would be better? Or maybe there is something genetic going on.

madman · May 14, 2017

JasonOnTRT said:
Finally, the test results are back. Here is a comparison of lab results along with subjective changes. For reference, I am 38 years old. My SHBG is currently at 17.4 nmol/l, down from 21.9 last summer.

10/25/2016
- T Cyp 80mg every 3.5 days (Shallow IM, 1/2" 28g insulin syringe)
- Anastrozole/DIM 0.5mg/200mg every 3.5 days
- HCG 250IU every other day
- DHEA 25mg twice daily

Total Testosterone: 584 (348-1197)
Free Testosterone: 21.1 (8.7-25.1)
Estradiol LC/MS: 10.7 (8.0-35.0)
DHT: 41 (30-85)

Feels like I'm injecting water. Some weight loss with heavy cardio. Body fat is 26.9%. Minimal to no changes in muscle. Energy/libido start dropping around noon and gone by 5-6pm. Pretty bad acne on back and shoulders. The AI obviously crashed my E2, that certainly doesn't help things but I felt the exact same over the summer as when E2 was in the 20's and 30's, so that wasn't the determining factor for not really feeling anything. I do feel better than not on TRT though. I stopped the AI for a couple of months after seeing these results. Over last summer/fall I had also tried 60, 70, and 75mg BIW before being increased to 80mg BIW that you see in these results. Every time the dose went up, Total T would come out lower and lower.

12/08/2016
- T Cyp 20mg every day (Sub-Q, 5/16" 30g insulin syringe)
- HCG 250IU every other day
- DHEA 25mg twice daily

Total Testosterone: 999 (348-1197)
Free Testosterone: 22 (8.7-25.1)
Estradiol LC/MS: 39.4 (8.0-35.0)
DHT: 47 (30-85)

A little bit more energy. No change in libido. Not really tired until 2-3pm and then energy drops off pretty fast. Less body fat (23.3%) and some muscle definition starting to appear. Still have acne, sometimes down to my biceps. I went from wearing large to medium shirts. Free T % is actually much lower now, but this is a small improvement.

4/25/2017
- T Prop 18mg every day (Sub-Q, 5/16" 30g insulin syringe)
- Anastrozole 0.125mg every 3.5 days
- HCG 250IU every other day
- DHEA 25mg twice daily

Total Testosterone: 712 (348-1197)
Free Testosterone: 17.1 (8.7-25.1)
Estradiol LC/MS: 20.9 (8.0-35.0)
DHT: 28 (30-85)

My energy level has definitely increased and there is maybe a little libido increase. I feel a lot more alert. Energy level stays high until 10-11pm, and I don't tire nearly as quickly doing activities like yard work and exercise. I feel like this is more like my younger self. Acne better. Body fat is lower (19.7%) and muscle definition has increased. There is more of a visual change in body composition. Maybe there is some truth to the Cypionate ester causing bloat that I've seen mentioned occasionally. You look at the daily T Cyp results and think that should be a lot better going by the numbers, but that was not te case at all. I just felt numb on T Cyp, even when around 700-800 range.

I've searched all over for lab comparisons involving different esters for guys who just aren't feeling the benefits of TRT that others do. Hopefully this helps some people out who are looking for a comparison. By the way, injecting Propionate does not sting at all in the small amounts that I'm using.

For me though, this raises even more questions. I'm actually a bit surprised at the Propionate results and how Total/Free T are not higher given the faster absorption. I expected much higher FT. There is not a lot of SHBG to bind to, and it obviously isn't converting to DHT or Estradiol. DHT and Estradiol actually fell off a cliff. Albumin is normal. Where is the T going? Maybe I metabolize it so fast that BID injections would be better? Or maybe there is something genetic going on.

Would have been nice to see the comparison between prop vs cyp everyday without an ai to see how it truly affected your e2. Your lower shbg affects your numbers regarding your total t. Good feedback regarding your protocols.