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Both. I discovered Hashimoto's in April of last year and I'm being treated by the same doctor who prescribed me topical testosterone. But I've read many studies linking autoimmune diseases to estrogen, so I don't doubt that it could be related to the high e2 levels after TRT. As soon as I...

I am very interested in your experience. Although we have in common the bad reactions to TRT and low SHBG, unlike you I have high cortisol, particularly at night, which was greatly aggravated by TRT and made the chronic insomnia I have had since I was 15 years old much worse. How is your...

Hello, do you have any updates on TRT in men with low SHBG? Since I started TRT in 2015, I have gained a lot of weight on my chest and below my belly button, subcutaneous fat and I feel very anxious. Since then, my insulin/glucose levels have gone up a lot in my tests, this insulin resistance...

This is not what my unsuccessful experience of 7 years with TRT, performing exams every 3 months approximately, shows me. Whenever my SHBG levels went down, estradiol and free testosterone went up a lot. The higher the dose of T, the greater the drop in shbg. More SHBG = less free testosterone...

To help those who still don't know Deca Only and Deca Base: - Deca Only: actually not only, as nandrolone does not aromatize in humans. They usually combine nandrolone + injectable estradiol or nandrolone + dhea (higher doses of dhea in men convert much more to e2 than to testosterone, unlike...

https://transfemscience.org/articles/nandrolone/ Congrats on the summary. You have touched the target points. Here's the best article I've read about the benefits of Nandrolone as HRT. It is an article aimed at the trans audience, but we also know that HIV patients often use nandrolone in place...

Nadrolone does not aromatize in humans, only in rats. This is the conclusion of all physicians who perform HRT with this compound on their patients. The Brazilian doctor Romulo Jogaib states that in 6 weeks of Deca Only the e2 will be zeroed. I confirmed this on my first try of HRT with Deca 1...

Your SHBG is high but below the upper limit. About the studies, search Pubmed for "SGBH TRT" there are many studies on improvement in patients with high SHBG, but virtually nothing on TRT in low SHBG. Both testosterone and the DHT derivative considerably decrease SHBG, increasing Free...

For me TRT worsens insulin sensitivity too much. Last year I was only able to lose weight on TRT with ozempic, as I said in my previous report. This year, I lost equivalent weight in the first 3 months of the year on the Carnivore Diet, high in protein and moderate in fat. Palumbo Keto Diet...

I don't think I posted this video here. If you can, try to put subtitles in English. This doctor is Brazilian and has good experience in the use of nandrolone as a testosterone substitute in patients who respond poorly to traditional TRT. He does a lot of tests on himself and makes videos or...

I don't respond well to dhea. Since I already have 2 children, I prefer not to use hcg.

I am 42 years old and have 25 years of chronic insomnia. 7 years of trt made sleep much worse. According to Dr Rand Mcclain, the main culprit is the altered cortisol after trt. Lately I gave up sleeping naturally and started to alternate between alprazolam and antihistamines. I notice that this...

If they are still active on the forum, please update us on microdosing protocols... Dr Chrysler recommended cyp 25mg/eod subq. The reports on jatenzo I've read so far, ed 2x, are excellent. The closest thing to jatenzo in injectable esters is propionate. In my test I varied between 10mg and...

Interesting, based on your statements, I searched my exam sheet and what you said happened. I did tests on trt, 250mg of sustanon/week, right after I started a cycle with stanozolol for 3 months, maintaining the dose of sustanon and redid the tests. FT dropped from 39 to 29. Shbg from 18 to 3.8...

I started today with 10mg, but this week I had already used enanthate and deca. Thought I'd test this dose a day. What do you think?

Follow my story. After 7 years going back and forth on TRT, I noticed that my insulin resistance got worse, I went to several doctors and nutritionists and I couldn't reduce my bf. I started Ozempic in Jan/22, in 3 months I lost approximately 8kg of fat and gained 2kg of muscle, according to bio...

Propionate Only is a protocol I intend to test in 2 weeks. According to a video I watched by Dr Rand Mcclain, some people tend to have higher cortisol elevations, he recommends 400 to 800mg of phosphatidylserine at night to bring it down.

I would love to see your insulin before and after. I think it crashed.

Great report! I'm on Carnivore Diet with that expectation as well. Definitely when you can control insulin everything changes. You've gone from insulin resistance to insulin sensitivity, which means that insulin has stopped anabolic fat cells and your body now uses your food much more...

Have you ever read an article that backs up your claim? Cuz as far as I know testosterone definitely lowers shbg. I believe your increase in shbg was related to the massive weight loss you've had.

There are studies in rats showing that deca decreases serotonin and dopamine, something good for those who have excess and obviously bad for those who have little. Testo is the opposite, I have the clear feeling that I am close to borderline bipolar, something I never had before TRT, but since I...

Have you tried increasing the ratio of one of the two to see if that changes?

Do you follow with propionate only? Were you able to resolve sleep? I've always been a night owl and I've also had sleep made worse by TRT but on cypionate, enanthate and sustanon. Until I watched an interview with Dr Rand Mcclain, saying that trt actually alters cortisol and that he...

I never used propionate separately, but whenever I used Sustanon I had swelling and pain that interfered with sleeping. A Brazilian bodybuilder says that to remove the pain from Sustanon or Propionate, just shake the ampoule before applying. Have you tried this technique?

Was the decrease in fat after the Deca + Testo protocol, 4:1?

Apparently it's the best protocol for guys with low shbg, i.e. who will have a lot more FT, FE2 and more side effects. How is your bf? Update us on bf changes going forward.

Have you tried propionate?

Yes, I feel better on the Carnivore Diet, but it only has an effect on weight loss when I'm off TRT. I'm going to test Deca 4:1 Enantato with the Carnivore Diet and depending on the results, I'll switch to propionate in daily microdoses.

I didn't know about brupopiona, thanks. I've already experimented with DIAMOX, which is used a lot in Mountain Sickness and apnea too, from what I've read it has a similar effect of increasing CO2, but I wasn't successful. I don't have central apnea, just obstructive, verified in polysomnography...

I started trt at age 35 (42 today), had mild apnea and weighed 84kg. After the TRT my sleep got a lot worse, but I didn't do another polysomnogram, but I believe it got worse. And I gained weight in my chest and belly, despite diet and training. I also gained muscle, but I notice that the trt...

Very good to know that you reversed the apnea with propionate. Soon I want to test this protocol, because I also have apnea and it gets much worse with Enanthate, Cypionate or Sustanon.