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Does anyone have any experience with feverfew? There appears to be some data to suggest it’s an effective supplement in the prevention of migraines. I just started it to see if it will blunt my tendency to get a headache with many forms of TRT. I will report back in a bit if anyone is interested.

Background: There is no shortage of threads and posts on nandrolone. Further, there are numerous opinions on the mental side effects of nandrolone. However, personal anecdotes vary widely with respect to how nandrolone affects mood. Like all hormones, nandrolone's affect one's physiology...

More and more, I believe I fall into the camp of those that feels better with E2 in the normal (non trt) range. Supposedly tetracyclines can raise estrogen levels. I know nothing about the mechanism. But, on two occasions, I have developed symptoms I believe to be E2 related while on Sarecycline...

There are a few threads on headaches, but I thought I’d start one dedicated for anyone who wants to solicit or provide advice and feedback on headaches. If you previously had or currently still experience headaches, please share your thoughts here. I am prone to headaches and have been my whole...

While there are already a lot of cream threads, it seems like there may be a high attrition rate - guys that use it and later bail on it for various reasons. The point if this poll is to try to discern how many guys are committed to cream in the long term. Hopefully, this poll will also give...

Gentlemen, My free T (details below) is in the middle of normal range per Quest. But, I feel really sluggish and I am working on figuring out (a) why? and, (b) how to treat it? I am trying to get a sense of where most guys feel "optimal" relative to their free T. I know there are a myriad of...

I recently discovered a surprising source of anxiety for me and wanted to share my experience so it may help others. It took me a month or so to figure out that over the counter CoQ10 was causing me recurring bouts of anxiety and tachycardia as well as episodic insomnia. I was really surprised...

Most of us wind up here because of struggles of one sort or another. I thought it might be useful to start a thread based purely on success stories. If this already exists, please disregard. Are you doing awesome? If so, please share your protocol and how long you have been doing awesome...

I have posted a lot of my struggles with TRT, mostly due to headaches caused by injections. But, I have also noticed another side effect that has been pretty consistent: nausea. Sometimes, but not always, I experience nausea 8-12 hours after I inject. It can last at least until the following...

Has anyone ever thought about trying to control DHT levels? I am aware of the post finasteride horror stories, but I am wondering if there is some way to reasonably reduce or limit DHT conversion? I wonder if excessive DHT plays a role in those who struggle with the myriad of TRT side effects...

I just posted some thoughts on blood pressure in this thread, and thought the topic was important enough to start its own thread. Please feel free to merge this thread with another if it already exists. I am looking for volunteers willing to watch their blood pressure. I have started to observe...

For me, one of the biggest upsides to TRT has been better energy. However, I sometimes wonder if I should be content with the energy I have? I am currently 49. I get up pretty early - usually 5-6AM every day. I drink a decent amount of coffee, but am done by around 8AM. I use Natesto three...

I know this topic has been beaten to death and with a little legwork, I am sure to find dozens of threads on this, so I apologize. But, like many here, I am still perplexed on why most forms of TRT I have tried cause side effects that outweigh the benefits. I have a ton of posts out there, but...

@madman, @Cataceous, @readalot or anyone else smarter than me, can you point me in the right direction? I am currently trialing small doses of enanthate mixed with grapeseed oil. I am tracking how I feel over time and trying to correlate it to expected testosterone levels. I am interested in...

Welcome to the Natesto thread. I have used Natesto on an off for several years, but it seems to be one of the less popular TRT options here. That said, I have seen a few readers mention it, and I thought it would be good to start a dedicated thread on Natesto where people can share their...

For reasons described here, I would like to gather information on who is using one of the commercial transdermal products. Please post feedback on your experience (successes or failures).

I have been on various forms of TRT and I am still fine tuning the ideal protocol. I am starting to believe that the "less is more" approach is wise. Years ago, I was on Hcg monotherapy and realized this did not work well for me. But, I have always been on some form of Hcg along with whatever...

I am in a gray area with borderline labs that functional medicine doctors would say may benefit from thyroid meds. I have started and stopped T3 a few times, primarily due to side effects. My biggest concern is I have noticed a low grade headache. Either my body does not want or need extra T3...

I will preface this by admitting I am slightly leery of my need for thyroid supplementation. My Free T3 and T4 are within normal range, but on the low end. My rT3 is a bit high and my rT3 to T3 ratio favors supplementation according to functional medicine guidance. In any case, I am open to to...

Does anyone here have any opinions (scientific or anecdotal) on the shelf life of testosterone creams? I have a cream from a local pharmacy that was compounded in 12/2019. I know the "official" answer is to throw it away, but I am curious if anyone here has any experience with this...

It is commonly accepted that one should take thyroid medication on an empty stomach. There is also research that demonstrates reduced absorption of certain thyroid medications if taken with coffee. But, from what I can tell, this has only been studied for T4. I could not find any information in...